2. Signaling Pathways
  3. Anti-infection
  4. HSV

HSV

Herpes simplex virus

HSV

Related Products

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HSV (Herpes simplex virus) can be spread when an infected person is producing and shedding the virus. Herpes simplex can be spread through contact with saliva, such as sharing drinks. Symptoms of herpes simplex virus infection include watery blisters in the skin or mucous membranes of the mouth, lips or genitals. Lesions heal with ascab characteristic of herpetic disease. As neurotropic and neuroinvasive viruses, HSV-1 and -2 persist in the body by becoming latent and hiding from the immune system in the cell bodies of neurons. After the initial or primary infection, some infected people experience sporadic episodes of viral reactivation or outbreaks.

HSV Isoform Specific Products:

HSV Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-13966S3
    2-Deoxy-D-glucose-13C6
    		Inhibitor
    2-Deoxy-D-glucose-13C6 (2-DG-13C6) is 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.
    2-Deoxy-D-glucose-<sup>13</sup>C<sub>6</sub>
  • HY-N7346
    Lucidadiol
    		Inhibitor
    Lucidadiol is a natural compound isolated from Ganoderma lucidum. Lucidadiol exhibits acetylcholinesterase-inhibitory activity, with IC50 values of 31 μM. Lucidadiol shows antiviral activity against influenza virus type A and HSV type 1.
    Lucidadiol
  • HY-17422D
    Acyclovir hydrochloride
    		Inhibitor
    Acyclovir (Aciclovir) hydrochloride is a potent, orally active antiviral agent. Acyclovir hydrochloride has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir hydrochloride induces cell cycle perturbation and apoptosis. Acyclovir hydrochloride prevents bacterial infections during induction therapy for acute leukaemia.
    Acyclovir hydrochloride
  • HY-A0061R
    Trifluridine (Standard)
    		Inhibitor
    Trifluridine (Standard) is the analytical standard of Trifluridine. This product is intended for research and analytical applications. Trifluridine (Trifluorothymidine) is an irreversible and orally active thymidylate synthase inhibitor, and thereby suppressing DNA synthesis. Trifluridine is an antiviral molecule used for research of HSV, rhabdovirus and orthopoxvirus infection. Trifluridine induces cell apoptosis and autophagy. Trifluridine is also an anticancer agent used in studies of metastatic colorectal cancer, gastrointestinal tumors.
    Trifluridine (Standard)
  • HY-B1268R
    Docusate (Sodium) (Standard)
    		Inhibitor
    Docusate (Sodium) (Standard) is the analytical standard of Docusate (Sodium). This product is intended for research and analytical applications. Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is one of the main components in stool softeners. Docusate Sodium is a sulfated surfactant and may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. Docusate Sodium is effective in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is an obesogen. Docusate Sodium with developmental exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipidemia in offspring fed a standard diet in mice.
    Docusate (Sodium) (Standard)
  • HY-B1357R
    Digitoxin (Standard)
    Digitoxin (Standard) is the analytical standard of Digitoxin. This product is intended for research and analytical applications. Digitoxin is an anti-cancer agent. Digitoxin induces apoptosis, inhibits influenza cytokine storm, causes DNA double-stranded breaks (DSBs) and blocks the cell cycle at the G2/M phase. Digitoxin induces calcium uptake into cells by forming transmembrane calcium channels and can be used for research of heart failure .
    Digitoxin (Standard)
  • HY-B1583R
    (Z)-Capsaicin (Standard)
    		Inhibitor
    (Z)-Capsaicin (Standard) is the analytical standard of (Z)-Capsaicin. This product is intended for research and analytical applications. (Z)-Capsaicin is the cis isomer of capsaicin, acts as an orally active TRPV1 agonist, and is used in the research of neuropathic pain.
    (Z)-Capsaicin (Standard)
  • HY-13605R
    Cytarabine (Standard)
    		Inhibitor
    Cytarabine (Standard) is the analytical standard of Cytarabine. This product is intended for research and analytical applications. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity.
    Cytarabine (Standard)
  • HY-17424R
    Penciclovir (Standard)
    		Inhibitor
    Penciclovir (Standard) is the analytical standard of Penciclovir. This product is intended for research and analytical applications. Penciclovir (VSA 671) is a potent and selective anti-herpesvirus agent with EC50 values of 0.5, 0.8 µg/ml for HSV-1 (HFEM), HSV-2 (MS), respectively. Penciclovir shows anti-herpesvirus activity with no-toxic. Penciclovir preventes mortality in mouse.
    Penciclovir (Standard)
  • HY-B2117R
    Valpromide (Standard)
    		Inhibitor
    Valpromide (Standard) is the analytical standard of Valpromide. This product is intended for research and analytical applications. Valpromide is an amide derivative of valproic acid and inhibits human epoxide hydrolase.
    Valpromide (Standard)
  • HY-B0277R
    Vidarabine (Standard)
    		Inhibitor
    Vidarabine (Standard) is the analytical standard of Vidarabine. This product is intended for research and analytical applications. Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses. Vidarabine has IC50s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2. Vidarabine also has anti-orthopoxvirus activity.
    Vidarabine (Standard)
  • HY-B0180R
    Imiquimod (Standard)
    		Inhibitor
    Imiquimod (Standard) is the analytical standard of Imiquimod. This product is intended for research and analytical applications. Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19.
    Imiquimod (Standard)
  • HY-130369
    NSC10010 hydrochloride
    		Inhibitor
    NSC10010 hydrochloride inhibits gammaherpesvirus associated B-lymphomas growth through activation of NF-kB and c-Myc-mediated signaling pathways. NSC10010 hydrochloride induces necrotic cell death in gammaherpesvirus infected B-cells. NSC10010 hydrochloride is also an inhibitor of Mtb ClpC1 ATPase.
    NSC10010 hydrochloride
  • HY-B0180C
    Imiquimod dihydrochloride
    		Inhibitor
    Imiquimod (R 837) dihydrochloride, an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19.
    Imiquimod dihydrochloride
  • HY-170547
    DNA polymerase-IN-6
    		Inhibitor
    DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, and inhibits HCMV, HSV-1, HSV-2 and EBV with EC50s of 0.33, 1.9, 0.76 and 0.066 µM, respectively.
    DNA polymerase-IN-6
  • HY-164343
    17,17-Ethylendioxyandrost-5-en-3β-ol
    		Inhibitor
    17,17-Ethylendioxyandrost-5-en-3β-ol is an HSV-1 inhibitor, with an EC50 value of 629 μM. 17,17-Ethylendioxyandrost-5-en-3β-ol can be used in research related to viral infections.
    17,17-Ethylendioxyandrost-5-en-3β-ol
  • HY-N2011R
    Octyl gallate (Standard)
    		Inhibitor 99.81%
    Octyl gallate (Standard) is the analytical standard of Octyl gallate. This product is intended for research and analytical applications. Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity. Octyl gallate (Progallin O) shows selective and sensitive fluorescent property. Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus.
    Octyl gallate (Standard)
  • HY-107801R
    Inosine pranobex (Standard)
    		Inhibitor
    Inosine pranobex (Standard) is the analytical standard of Inosine pranobex. This product is intended for research and analytical applications. Inosine pranobex is an orally active immunomodulator. Inosine pranobex has broad-spectrum antiviral activity. Inosine pranobex inhibits human immunodeficiency virus (HIV), herpes simplex virus (HSV), vaccinia virus (VACV), human tumor virus (HPV), Cytomegalovirus, influenza virus (INFV), parainfluenza virus (PIV), and Epstein-Barr virus .
    Inosine pranobex (Standard)
  • HY-15303S
    Pritelivir-d4-1
    		Inhibitor
    Pritelivir-d4-1 (AIC316-d4-1) is deuterium labeled Pritelivir. Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2.
    Pritelivir-d<sub>4</sub>-1
  • HY-150306
    IM-250
    		Inhibitor 99.94%
    IM-250 is an orally active helicase-primase inhibitor. IM-250 is effective against HSV infection. IM-250 inhibits HSV-1 infection in Vero cells (IC50: ~20 nM).
    IM-250
HSV Isoform Comparison

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