2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N1201S
    Apigenin-d5
    		98.90%
    Apigenin-d5 is a deuterated labeled Apigenin. Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM.
    Apigenin-d<sub>5</sub>
  • HY-N0473R
    L-Tyrosine (Standard)
    L-Tyrosine (Standard) is the analytical standard of L-Tyrosine. This product is intended for research and analytical applications. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
    L-Tyrosine (Standard)
  • HY-W013078
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate
    		≥98.0%
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate is an endogenous metabolite.
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate
  • HY-107854S
    N-Acetyl-5-hydroxytryptamine-d3
    		≥98.0%
    N-Acetyl-5-hydroxytryptamine-d3 is the deuterium labeled N-Acetyl-5-hydroxytryptamine. N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor[1][2].
    N-Acetyl-5-hydroxytryptamine-d<sub>3</sub>
  • HY-134313
    8-NH2-ATP
    8-NH2-ATP, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado is reported to be potent as shown by induction of apoptosis-related cleavage of poly (ADP-ribose) polymerase.
    8-NH2-ATP
  • HY-W014423S
    L-Histidine-13C hydrochloride hydrate
    		98.00%
    L-Histidine-13C (hydrochloride hydrate) is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
    L-Histidine-<sup>13</sup>C hydrochloride hydrate
  • HY-126354
    Palmitoyldocosahexaenoyl phosphatidylcholine
    		≥99.0%
    Palmitoyldocosahexaenoyl phosphatidylcholine is an endogenous metabolite.
    Palmitoyldocosahexaenoyl phosphatidylcholine
  • HY-D0885A
    Sodium creatine phosphate dibasic tetrahydrate
    		≥98.0%
    Phosphocreatine disodium tetrahydrate, primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives, is a substrate for the determination of creatine kinase and used to regenerate ATP during skeletal muscle contraction.
    Sodium creatine phosphate dibasic tetrahydrate
  • HY-W010382R
    Oxaloacetic acid (standard)
    Oxaloacetic acid (Standard) is the analytical standard of Oxaloacetic acid. This product is intended for research and analytical applications. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function.
    Oxaloacetic acid (standard)
  • HY-N2325R
    D-(+)-Cellobiose (Standard)
    D-(+)-Cellobiose (Standard) is the analytical standard of D-(+)-Cellobiose. This product is intended for research and analytical applications. D-(+)-Cellobiose is an endogenous metabolite.
    D-(+)-Cellobiose (Standard)
  • HY-E70033
    D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP)
    D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP) is a member of CAZy glycoside hydrolase GH112 family, is often used in biochemical studies. D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP) catalyses the phosphorolysis of lacto-n-biose and galacto-n-biose, to produce Gal-1-P and the corresponding N-acetyl-D-hexosamine.
    D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP)
  • HY-B1659R
    Glycerol (Standard)
    Glycerol (Standard) is the analytical standard of Glycerol. This product is intended for research and analytical applications. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis.
    Glycerol (Standard)
  • HY-30215R
    (S)-Leucic acid (Standard)
    (S)-Leucic acid (Standard) is the analytical standard of (S)-Leucic acid. This product is intended for research and analytical applications. (S)-Leucic acid is an amino acid metabolite.
    (S)-Leucic acid (Standard)
  • HY-W009216R
    2'-Deoxycytidine-5'-monophosphoric acid (Standard)
    2'-Deoxycytidine-5'-monophosphoric acid (Standard) is the analytical standard of 2'-Deoxycytidine-5'-monophosphoric acid. This product is intended for research and analytical applications. 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
    2'-Deoxycytidine-5'-monophosphoric acid (Standard)
  • HY-W654264
    2-Methylbutyrylcarnitine chloride
    2-Methylbutyrylcarnitine (chloride) is a gut microbial metabolite which binds to integrin α2β1 in platelets, potentiating cytosolic phospholipase A2 (cPLA2) activation and platelet hyperresponsiveness. 2-Methylbutyrylcarnitine (chloride) enhances platelet hyperreactivity and thrombus formation in mice. 2-Methylbutyrylcarnitine (chloride) is a branched-chain acylcarnitine.
    2-Methylbutyrylcarnitine chloride
  • HY-113313S
    Aldosterone-d8
    		99.8%
    Aldosterone-d8 is a deuterium labeled Aldosterone. Aldosterone, produced in the adrenal zona glomerulosa, regulates blood pressure[1].
    Aldosterone-d<sub>8</sub>
  • HY-W014930R
    DL-5-Hydroxylysine hydrochloride (Standard)
    DL-5-Hydroxylysine (hydrochloride) (Standard) is the analytical standard of DL-5-Hydroxylysine (hydrochloride). This product is intended for research and analytical applications. DL-5-Hydroxylysine hydrochloride is an endogenous metabolite.
    DL-5-Hydroxylysine hydrochloride (Standard)
  • HY-W008253S
    5-Hydroxyindole-3-acetic acid-d2
    		99.00%
    5-Hydroxyindole-3-acetic acid-d2 is the deuterium labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.
    5-Hydroxyindole-3-acetic acid-d<sub>2</sub>
  • HY-Y0771
    3,4-Dimethoxyphenylacetic acid
    		99.46%
    3,4-Dimethoxyphenylacetic acid is a building block in the chemical synthesis.
    3,4-Dimethoxyphenylacetic acid
  • HY-N10220
    Paraherquamide E
    Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects.
    Paraherquamide E
Cat. No. Product Name / Synonyms Application Reactivity