2. Signaling Pathways
  3. Immunology/Inflammation
  4. Mucin

Mucin

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P99634
    Gatipotuzumab
    Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 (TA-MUC1). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC).
    Gatipotuzumab
  • HY-B0264
    Guaifenesin
    		99.82%
    Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough.
    Guaifenesin
  • HY-P99962
    Surzebiclimab
    Surzebiclimab (BGB-A425) is a humanized IgG1-variant monoclonal antibody against T-cell immunoglobulin and mucin-domain containing-3 (TIM-3). Surzebiclimab binds to the extracellular domain of human Tim-3 with high affinity (KD=0.36 nM) and specificity. Surzebiclimab can be used in research of cancer.
    Surzebiclimab
  • HY-160109
    Ac5GalNTGc
    		98.39%
    Ac5GalNTGc is a analog of hexosamine. Ac5GalNTGc inhibits mucin-type O-linked glycosylation biosynthesis.
    Ac5GalNTGc
  • HY-P2508
    MUC1, mucin core
    		99.85%
    MUC1, mucin core is the region of the MUC1 mucin core. MUC1 is a type I transmembrane glycoprotein, and is overexpressed and aberrantly glycosylated in carcinoma cells. MUC1, mucin core protein binds to domain 1 of ICAM-1.
    MUC1, mucin core
  • HY-158333
    Tasuldine
    		Inhibitor
    Tasuldine is a mucolytic agent, which decreases the sialomucin content of mucus, improves mucociliary and cough clearance.
    Tasuldine
  • HY-159702
    Eudragit RS 100
    		Activator
    Eudragit RS 100 is a mucoadhesive, nonbiodegradable positively charged polymer,which can be used for research of developing nanoparticles (NPs) for the ophthalmic and oral administration of Ibuprofen (HY-78131) and Cyclosporins (HY-100731), as well as nano- and micro-fibres used as scaffolds. Eudragit RS 100 NPs interacts efficiently with mucin and promotes glutathione (GSH) transmucosal absorption.
    Eudragit RS 100
  • HY-P99968
    Clivatuzumab
    		Inhibitor ≥99.0%
    Clivatuzumab is a humanized anti-mucin monoclonal antibody targeting an epitope in the MUC1 antigen expressed in most pancreatic cancers.
    Clivatuzumab
  • HY-B2206
    Gefarnate
    		≥98.0%
    Gefarnate is a agent used for the treatment of gastritis and gastric ulcer, and has been proposed for use in the treatment of dry eye syndrome.
    Gefarnate
  • HY-P0280
    MUC5AC motif peptide
    		98.79%
    MUC5AC motif peptide is a 16-amino acid fragment of mucin 5.
    MUC5AC motif peptide
  • HY-160109A
    Ac5GalNTGc epimer
    		Inhibitor 98.39%
    Ac5GalNTGc epimer is an analogue of hexosamine and the racemate of Ac5GalNTGc (HY-160109). Ac5GalNTGc inhibits mucin-type O-linked glycosylation biosynthesis.
    Ac5GalNTGc epimer
  • HY-160060
    MA3 aptamer sodium
    		Chemical
    MA3 aptamer sodium is an 86-base long DNA aptamer targeting the mucin MUC1. MA3 aptamer sodium binds to the peptide epitope of mucin 1 (MUC1) with a Kd of 38.3 nM and has minimal cross-reactivity with albumin.
    MA3 aptamer sodium
  • HY-160062
    S2.2 aptamer sodium
    		Chemical
    S2.2 aptamer sodium is a nucleic acid aptamer targeting the mucin MUC1 and can be used for targeted imaging of MCF-7 cancer cells. S2.2 aptamer sodium was labeled with Cy5, and when fluorescent silicon nanodots (SiND) were present, the fluorescence was quenched; when MUC1 was also present, the fluorescence was restored. S2.2 aptamer sodium detects MUC1 with a linear range of 3.33-250 nM.
    S2.2 aptamer sodium
Cat. No. Product Name / Synonyms Application Reactivity