PROTACs Chemical

PROTACs Isoform Comparison

PROTACs Chemicals (6):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

MS21	2376137-05-0	99.88%
MS21, a novel degrader of AKT, selectively inhibits the growth of PI3K/PTEN pathway-mutant cancers with wild-type KRAS and BRAF.

PROTAC CDK9 degrader-4	2411021-01-5	98.38%
PROTAC CDK9 degrader-4 is a highly potent and efficacious CDK9 degrader for targeting transcription regulation.

MS83	2762181-19-9
MS83 is a proof-of-concept PROTAC by linking the KEAP1 ligand to a BRD4/3/2 binder.

Folate-MS432	2769735-56-8
Folate-MS432, a PROTAC, is capable of degrading MEKs in a folate receptor-dependent manner in cancer cells.

CFT-2718
CFT-2718 is a new BRD4-targeting degrader (PROTAC) with enhanced catalytic activity and in vivo properties.

ZXH-4-137	2711006-74-3
ZXH-4-137 is a potent and selective CRBN degrader (PROTAC).

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