2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Phosphodiesterase (PDE)
  5. Autotaxin Isoform

Autotaxin

 

Autotaxin Related Products (29):

Cat. No. Product Name Effect Purity
  • HY-123637
    Autotaxin-IN-1
    		Inhibitor
    Autotaxin-IN-1 is a potent autotaxin inhibitor, which has favorable potency (IC50=2.2 nM), PK properties, and a robust PK/PD relationship. Autotaxin-IN-1 is used in treatment of osteoarthritis pain.
  • HY-143581
    ATX inhibitor 8
    		Inhibitor
    ATX inhibitor 8 is a Autotaxin (ATX) inhibitor extracted from patent WO2018212534A1 compound 96.
  • HY-135089
    Autotaxin-IN-5
    		Inhibitor
    Autotaxin-IN-5 (compound 63), extracted from patent WO2018212534A1, is an Autotaxin inhibitor. Autotaxin-IN-5 has the potential to treat idiopathic pulmonary fibrosis.
  • HY-150614
    Autotaxin-IN-6
    		Inhibitor
    Autotaxin-IN-6 (compound 23) is a potent autotaxin (ATX) inhibitor with an IC50 value of 30 nM. Autotaxin-IN-6 can reduce cell migration. Autotaxin-IN-6 can be used for researching anticancer.
  • HY-158001
    MHC00188
    		Inhibitor
    MHC00188 is an allosteric inhibitor for Autotaxin (ATX) with an IC50 of 2.53 μM.
  • HY-143237
    ATX inhibitor 11
    		Inhibitor
    ATX inhibitor 11 (compound 13c) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker α-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research.
  • HY-146124
    ATX inhibitor 21
    		Inhibitor
    ATX inhibitor 21 (compound 8) is a potent ATX (autotaxin) inhibitor, with an IC50 of 3490 nM.
  • HY-149018
    ATX inhibitor 22
    		Inhibitor
    ATX inhibitor 22 is a novel inhibitor of ATX (autotaxin) with IC50 of 218 nM but lost its inhibitory activity of LPAR1.
  • HY-149716
    MEY-003
    MEY-003 is an Autotaxin(ATX) inhibitor with EC50s of 460 nM and 1.09 μM for hATX-β and hATX-ɣ (analysis with LPC18:1). MEY-003 behaves as a non-competitive inhibitor with K iof 432 nM. MEY-003 can be used for targeted ATX-related disease research .