2. Signaling Pathways
  3. Immunology/Inflammation
  4. CD19
  5. CD19 Inhibitor

CD19 Inhibitor

CD19 Inhibitors (7):

Cat. No. Product Name Effect Purity
  • HY-P9963
    Blinatumomab
    		Inhibitor
    Blinatumomab (Anatumomab) is a bispecific monoclonal antibody with two binding sites, one for CD3E on T cells and one for CD19 on B cells. Blinatumomab can be used in research for acute lymphoblastic leukemia.
  • HY-P99113
    Inebilizumab
    		Inhibitor 99.00%
    Inebilizumab is an anti-CD19 monoclonal antibody (mAb) with enhanced antibody-dependent cell-mediated cytotoxicity against B cells. Inebilizumab can be used for multiple sclerosis and neuromyelitis optica research.
  • HY-P99711
    Loncastuximab
    		Inhibitor
    Loncastuximab (RB4v1.2) is an anti-CD19 monoclonal antibody. Loncastuximab shows antitumor activity and has potential application in non-Hodgkin's lymphoma (NHL), including diffuse large B-cell lymphoma (DLBCL).
  • HY-P99761
    Obexelimab
    		Inhibitor
    Obexelimab (XmAb5871) is a humanized anti-CD19 antibody. Obexelimab works by inhibiting B cell receptor (BCR) mediated calcium influx and promoting the phosphorylation of Fc γ receptor IIb (FcγRIIb), which reduces B cell activation and function, leading to B cell apoptosis. Obexelimab can be used in research for rheumatoid arthritis and systemic lupus erythematosus.
  • HY-P99285
    Denintuzumab
    		Inhibitor
    Denintuzumab (hBU 12) is a recombinant humanized anti-CD19 monoclonal antibody. Denintuzumab can be used as the antibody moiety (ADC antibody) of antibody-drug conjugates to synthesize ADC, Denintuzumab Mafodotin (SGN-CD19A). Denintuzumab Mafodotin can be used in the research of acute lymphoblastic leukemia.
  • HY-P99976
    Anti-Mouse CD19 Antibody (1D3)
    		Inhibitor
    Anti-Mouse CD19 Antibody (1D3) is an anti-mouse CD19 IgG2a antibody inhibitor.
  • HY-P990017
    Englumafusp alfa
    		Inhibitor
    Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion construct comprised of a CD19-specific antibody domain fused to a trimerized extracellular domains of human 41BBL. Englumafusp alfa promotes CD19-specific 4-1BB cross-linking on the surface of T and NK cells.