2. Immunology/Inflammation
  3. CD19
  4. Blinatumomab

Blinatumomab  (Synonyms: Anatumomab)

Cat. No.: HY-P9963

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Blinatumomab (Anatumomab) is a bispecific monoclonal antibody with two binding sites, one for CD3E on T cells and one for CD19 on B cells. Blinatumomab can be used in research for acute lymphoblastic leukemia.

For research use only. We do not sell to patients.

CAS No. : 853426-35-4

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5 mg USD 3600 In-stock
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Based on 1 publication(s) in Google Scholar

Blinatumomab Related Antibodies

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1 Publications Citing Use of MCE Blinatumomab

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Description

Blinatumomab (Anatumomab) is a bispecific monoclonal antibody with two binding sites, one for CD3E on T cells and one for CD19 on B cells. Blinatumomab can be used in research for acute lymphoblastic leukemia[1][2][3][4].

Isotype

(scFv-kappa-heavy)-(scFv-heavy-kappa)
Species

Human
In Vivo

Blinatumomab (0.01-1 μg, i.v. once daily for 5 days) extended the survival of mice in a dose-dependent manner in a leukemic nonobese diabetic SCID mouse model[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: leukemic nonobese diabetic SCID mouse model (20 days old)[2]
Dosage: 0.01-1 μg
Administration: Intravenous injection (i.v.), once daily for 5 days
Result: Caused none of the animals developed detectable tumors and survived inoculation of NALM-6 cells at cumulative doses of 5 or 0.5 μg for the entire observation period of 76 days. Cumulative doses of 0.05 and 0.005 μg were not effective in preventing tumor growth.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Blinatumomab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • (scFv-kappa-heavy)-(scFv-heavy-kappa)
Purity & Documentation
References
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Blinatumomab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Blinatumomab853426-35-4AnatumomabCD19bispecific monoclonal antibodyacute lymphoblastic leukemiaInhibitorinhibitorinhibit

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