2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. FBPase
  5. FBPase Inhibitor

FBPase Inhibitor

FBPase Inhibitors (7):

Cat. No. Product Name Effect Purity
  • HY-16307
    MB05032
    		Inhibitor 99.66%
    MB05032 is a special and efficacious gluconeogenesis inhibitor targeted the AMP binding site of fructose 1,6-bisphosphatase (FBPase) with an IC50 value of 16 nM.
  • HY-136717
    FBPase-1 inhibitor-1
    		Inhibitor 99.10%
    FBPase-1 inhibitor-1 (compound 1) is a allosteric inhibitor of fructose-1,6-bisphosphatase (FBPase-1).
  • HY-14955
    Managlinat dialanetil
    		Inhibitor 98.13%
    Managlinat dialanetil (MB06322) is an orally bioavailable inhibitor of fructose 1,6-bisphosphatase (FBPase) for the treatment of type 2 diabetes .
  • HY-146725
    FBPase-IN-1
    		Inhibitor 98.30%
    FBPase-IN-1 is a potent FBPase (Fructose-1,6-bisphosphatase) inhibitor for Type 2 diabetes (T2D) study with an IC50 of 0.22 μM. FBPase-IN-1 can reduce blood glucose levels and ameliorate glucose tolerance. FBPase-IN-1 modifies the C128 site, regulates the N125-S124-S123 allosteric pathway of FBPase and affects the catalytic activity of FBPase.
  • HY-168103
    FBPase-IN-3
    		Inhibitor
    FBPase-IN-3 (compound 45) is a FBPase (fructose-1,6-bisphosphatase) inhibitor with an IC50 of 2.08 μM. FBPase-IN-3 exhibits potent inhibitory activity of gluconeogenesis.
  • HY-168651
    FBPase-IN-4
    		Inhibitor
    FBPase-IN-4 (Compound 11 n) is a potent FBPase (Fructose-1,6-bisphosphatase) inhibitor with a Ki value of 1.78 μM. FBPase-IN-4 can be used in type 2 diabetes research.
  • HY-147645
    FBPase-IN-2
    		Inhibitor
    FBPase-IN-2 (HS36) is a potent Fructose-1,6-bisphosphatase (FBPase) covalent inhibitor with an IC50 of 0.15 μM. FBPase-IN-2 reduces glucose production in hepatocytes. FBPase-IN-2 can be used for type 2 diabetes mellitus research.