2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. GLUT

GLUT

Glucose transporter

GLUT

Related Products

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GLUTs (Glucose transporters ) are proteins comprising 12 membrane-spanning regions. GLUTs transport glucose across the plasma membrane by means of a facilitated diffusion mechanism.

GLUT1 (SLC2A1), a uniporter protein, facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranes. GLUT3 (SLC2A3), mainly present in the brain, has high affinity for glucose. GLUT3 facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT4 (SLC2A4) is found in the heart, skeletal muscle, adipose tissue, and brain. GLUT4 is an insulin-responsive glucose transporter.

GLUT Isoform Specific Products:

GLUT Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-152033
    URAT1 inhibitor 4
    		Inhibitor
    URAT1 inhibitor 4, a Lesinurad derivative, is a potent and orally active URAT1 inhibitor with an IC50 of 7.56 μM. URAT1 inhibitor 4 has higher in vivo urate-lowering efficacy than Lesinurad (HY-15258).
    URAT1 inhibitor 4
  • HY-N0222R
    Avicularin (Standard)
    		Inhibitor
    Avicularin (Standard) is the analytical standard of Avicularin. This product is intended for research and analytical applications. Avicularin is an orally active flavonoid. Avicularin inhibits NF-κB (p65), COX-2 and PPAR-γ activities. Avicularin has anti-inflammatory, anti-infectious anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities.
    Avicularin (Standard)
  • HY-N6936
    Sennidin A
    		Activator
    Sennidin A, isolated from the leaves of Cassia angustifolia, inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation.
    Sennidin A
  • HY-N6935R
    Sennidin B (Standard)
    		Activator
    Sennidin B (Standard) is the analytical standard of Sennidin B. This product is intended for research and analytical applications. Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .
    Sennidin B (Standard)
  • HY-163139
    Physagulide Y
    		Inhibitor
    Physagulide Y (2), a withanolide with anticancer activity, is a GLUT1 inhibitor.
    Physagulide Y
  • HY-121086
    BAY-588
    BAY-588 is a selective inhibitor of GLUT1 with an IC50 value of 1.18μM.
    BAY-588
Cat. No. Product Name / Synonyms Application Reactivity
GLUT Isoform Comparison

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.