2. Signaling Pathways
  3. GPCR/G Protein
  4. Neuropeptide FF Receptor
  5. Neuropeptide FF Receptor Agonist

Neuropeptide FF Receptor Agonist

Neuropeptide FF Receptor Isoform Comparison

Neuropeptide FF Receptor Agonists (3):

Cat. No. Product Name Effect Purity
  • HY-P10377
    GUB03385
    		Agonist
    GUB03385 is a long-acting PrRP31 analogue. GUB03385 is a potent dual agonist for GPR10 (full agonist, EC50: 0.4 nM) and NPFF2R (partial agonist, EC50: 20 nM). GUB03385 has anti-obesity effect.
  • HY-P10379
    palm-PrRP31
    		Agonist
    palm-PrRP31 is a potent dual receptor agonist for both GPR10 (EC50=72 pM) and NPFF-R2. palm-PrRP31 activates downstream signaling pathways through binding to its receptors, GPR10 and NPFF-R2, which results in reduced appetite and increased energy expenditure. Utilizing palm-PrRP31 facilitates the study of the mechanism of action in the nervous system, thereby elucidating the complex biological processes that regulate appetite and energy expenditure.
  • HY-P10380
    palm11-PrRP31
    		Agonist
    palm11-PrRP31 is a lipidized endogenous appetite inhibitory neuropeptide (PrRP) analogue. palm11-PrRP31 is GPR10 (EC50=39 pM) and NPFF-R2 effective dual agonists. palm11-PrRP31 is able to mimic the natural function of PrRP by binding to these receptors to reduce food intake. palm11-PrRP31 can be used as a potential anti-obesity agent and for the study of neuropeptide-receptor interaction.