2. Signaling Pathways
  3. Vitamin D Related/Nuclear Receptor
  4. Nuclear Hormone Receptor 4A/NR4A
  5. Nuclear Hormone Receptor 4A/NR4A Isoform
  6. Nuclear Hormone Receptor 4A/NR4A Activator

Nuclear Hormone Receptor 4A/NR4A Activator

Nuclear Hormone Receptor 4A/NR4A Activator (1):

Cat. No. Product Name Effect Purity
  • HY-P1624A
    Teduglutide TFA
    		Activator
    Teduglutide TFA is a dipeptidyl peptidase IV resistant glucagon-like peptide 2 (GLP-2) analogue. Teduglutide TFA can activate the expression of nuclear receptor subfamily 4 group a member 1 (NR4a1)/nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide TFA can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis.