2. Signaling Pathways
  3. Nucleoside Transporters
  4. Nucleoside Transporters Inhibitor

Nucleoside Transporters Inhibitor

Nucleoside Transporters Inhibitors (7):

Cat. No. Product Name Effect Purity
  • HY-100957
    Dilazep dihydrochloride
    		Inhibitor 99.64%
    Dilazep dihydrochloride is an inhibitor of adenosine uptake. Dilazep dihydrochloride has cerebral and coronary vasodilating action through enhancement of effect of adenosine. Dilazep dihydrochloride also inhibits the ischemic damage, platelet aggregation, and membrane transport of nucleosides.
  • HY-112843
    CNT2 inhibitor-1
    		Inhibitor 98.77%
    CNT2 inhibitor-1 is a potent concentrative nucleoside transporter 2 Inhibitor (CNT2), with an IC50 of 640 nM for hCNT2.
  • HY-108322
    NBTGR
    		Inhibitor 99.13%
    NBTGR (p-Nitrobenzylthioguanosine) is a potent inhibitor of nucleoside transport; inhibits adenosine uptake with a Ki of 70 nM.
  • HY-116927
    KW-7158
    		Inhibitor
    KW-7158 is a putative afferent nerve inhibitor that can depress vesica-vascular reflexes in rats. KW-7158 is an inhibitor of nucleoside transporter-1 (ENT1/SLC29A1) and acts as an antagonist for overactive bladder (OAB).
  • HY-123718
    6-Benzylthioinosine
    		Inhibitor
    6-Benzylthioinosine is a compound with antileukemic activity that increases cytotoxicity against acute myeloid leukemia cells when combined with Metformin (HY-B0627), modulating cellular metabolism and signaling pathways through multiple mechanisms. 6-Benzylthioinosine is also a potential precursor inhibitor of mammalian nucleoside transporter ENT1 (es), and its derivatives have anti-Toxoplasma activity.
  • HY-124795
    FPMINT
    		Inhibitor
    FPMINT is a potent, irreversible and non-competitive inhibitor of Equilibrative nucleoside transporters (ENTs), which is more selective to ENT2 than to ENT1. FPMINT plays an important role in uridine uptake.
  • HY-115366
    Soluflazine
    		Inhibitor 98.86%
    Soluflazine is a nucleoside transport inhibitor with anticonvulsant action. Soluflazine can be used as an antiepileptic agent.