2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. (S)-3-Hydroxybutanoic acid

(S)-3-Hydroxybutanoic acid  (Synonyms: (S)-β-Hydroxybutanoic acid; L-(+)-3-Hydroxybutyric acid; L-β-Hydroxybutyric acid)

Cat. No.: HY-W050031 Purity: ≥97.0%
SDS
COA
Handling Instructions Technical Support

(S)-3-Hydroxybutanoic acid is a metabolite and a disease marker of depression. 3-Hydroxybutyric acid is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low.

For research use only. We do not sell to patients.

(S)-3-Hydroxybutanoic acid Chemical Structure

(S)-3-Hydroxybutanoic acid Chemical Structure

CAS No. : 6168-83-8

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in Water In-stock
Solid
50 mg In-stock
100 mg In-stock
500 mg In-stock
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5 g   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of (S)-3-Hydroxybutanoic acid:

(S)-3-Hydroxybutanoic acid Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

(S)-3-Hydroxybutanoic acid is a metabolite and a disease marker of depression. 3-Hydroxybutyric acid is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

(S)-3-Hydroxybutanoic acid affects the basal glucose uptake, and can be used as the alternative source of energy to glucose during fasting[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(S)-3-Hydroxybutanoic acid Related Antibodies
Molecular Weight

104.11

Formula

C4H8O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@H](O)CC(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (960.57 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 9.6057 mL 48.0284 mL 96.0569 mL
5 mM 1.9211 mL 9.6057 mL 19.2114 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥97.0%

SDS (393 KB)

COA (246 KB) HNMR (117 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 9.6057 mL 48.0284 mL 96.0569 mL 240.1422 mL
5 mM 1.9211 mL 9.6057 mL 19.2114 mL 48.0284 mL
10 mM 0.9606 mL 4.8028 mL 9.6057 mL 24.0142 mL
15 mM 0.6404 mL 3.2019 mL 6.4038 mL 16.0095 mL
20 mM 0.4803 mL 2.4014 mL 4.8028 mL 12.0071 mL
25 mM 0.3842 mL 1.9211 mL 3.8423 mL 9.6057 mL
30 mM 0.3202 mL 1.6009 mL 3.2019 mL 8.0047 mL
40 mM 0.2401 mL 1.2007 mL 2.4014 mL 6.0036 mL
50 mM 0.1921 mL 0.9606 mL 1.9211 mL 4.8028 mL
60 mM 0.1601 mL 0.8005 mL 1.6009 mL 4.0024 mL
80 mM 0.1201 mL 0.6004 mL 1.2007 mL 3.0018 mL
100 mM 0.0961 mL 0.4803 mL 0.9606 mL 2.4014 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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(S)-3-Hydroxybutanoic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-3-Hydroxybutanoic acid6168-83-8(S)-β-Hydroxybutanoic acidL-(+)-3-Hydroxybutyric acid L-β-Hydroxybutyric acidEndogenous Metabolitetype 2 diabeteobesityInhibitorinhibitorinhibit

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