α-MSH (Synonyms: α-Melanocyte-Stimulating Hormone)

Name: α-MSH
Brand: MedChemExpress
SKU: HY-P0252
Rating: 5.0 (14 reviews)

Cat. No.: HY-P0252 Purity: 99.57%: FAQs
Data Sheet SDS COA Handling Instructions

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α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC).

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α-MSH Chemical Structure

CAS No. : 581-05-5

Size	Price	Stock	Quantity
1 mg	USD 66	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 198	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 343	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 739	In-stock	Estimated Time of Arrival: December 31
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Based on 14 publication(s) in Google Scholar

Other Forms of α-MSH:

α-MSH free acid Get quote
α-MSH TFA Get quote

14 Publications Citing Use of MCE α-MSH

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MC1R MC3R MC2R MC4R MC5R

Biological Activity
Purity & Documentation
References
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Description

IC₅₀ & Target

MC4R

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	0.0027 μM Compound: alpha-MSH	Agonist activity at human recombinant MC3 receptor expressed in CHO cells assessed as cAMP accumulation by enzyme fragment complementation assay Agonist activity at human recombinant MC3 receptor expressed in CHO cells assessed as cAMP accumulation by enzyme fragment complementation assay	[PMID: 20329799]
CHO	EC₅₀	1.1 nM Compound: Alpha-MSH	Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 3 by radio labeled ligand assay (Displacement of [125I]NDP-alpha-MSH from the human receptors expressed in CHO cells) Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 3 by radio labeled ligand assay (Displacement of [125I]NDP-alpha-MSH from the human receptors expressed in CHO cells)	[PMID: 15982875]
CHO	EC₅₀	1.9 nM Compound: Alpha-MSH	Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 4 by radio labeled ligand assay (Displacement of [125I]NDP-alpha-MSH from the human receptors expressed in CHO cells) Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 4 by radio labeled ligand assay (Displacement of [125I]NDP-alpha-MSH from the human receptors expressed in CHO cells)	[PMID: 15982875]
CHO	IC₅₀	118 nM Compound: Alpha-MSH	Inhibition concentration (binding affinity) against human melanocortin receptor 5 by displacement of [125I]NDP-alpha-MSH from the human receptors expressed in CHO cells Inhibition concentration (binding affinity) against human melanocortin receptor 5 by displacement of [125I]NDP-alpha-MSH from the human receptors expressed in CHO cells	[PMID: 15982875]
CHO	EC₅₀	17 nM Compound: Alpha-MSH	Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 5 by radio labeled ligand assay (Displacement of [125I]NDP-alpha-MSH from the human receptors expressed in CHO cells) Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 5 by radio labeled ligand assay (Displacement of [125I]NDP-alpha-MSH from the human receptors expressed in CHO cells)	[PMID: 15982875]
CHO	IC₅₀	19 nM Compound: alpha-MSH	Concentration for 50% inhibition of human melanocortin-4 receptor expressed in CHO cells using [125I]NDP-alpha-MSH as radioligand Concentration for 50% inhibition of human melanocortin-4 receptor expressed in CHO cells using [125I]NDP-alpha-MSH as radioligand	[PMID: 15582434]
CHO	IC₅₀	19 nM Compound: Alpha-MSH	Inhibition concentration (binding affinity) against human melanocortin receptor 3 by displacement of [125I]NDP-alpha-MSH from the human receptors expressed in CHO cells Inhibition concentration (binding affinity) against human melanocortin receptor 3 by displacement of [125I]NDP-alpha-MSH from the human receptors expressed in CHO cells	[PMID: 15982875]
CHO	IC₅₀	19 nM Compound: Alpha-MSH	Inhibition concentration (binding affinity) against human melanocortin receptor 4 by displacement of [125I]NDP-alpha-MSH from the human receptors expressed in CHO cells Inhibition concentration (binding affinity) against human melanocortin receptor 4 by displacement of [125I]NDP-alpha-MSH from the human receptors expressed in CHO cells	[PMID: 15982875]
CHO	EC₅₀	2.2 nM Compound: alpha-MSH	Agonist activity at human recombinant MC4 receptor expressed in CHO cells by cAMP responsive beta lactamase reporter gene assay Agonist activity at human recombinant MC4 receptor expressed in CHO cells by cAMP responsive beta lactamase reporter gene assay	[PMID: 20329799]
HEK293	EC₅₀	0.0009 μM Compound: alpha-MSH	Agonist activity at human recombinant MC1 receptor expressed in HEK293 cells assessed as cAMP accumulation by enzyme fragment complementation assay Agonist activity at human recombinant MC1 receptor expressed in HEK293 cells assessed as cAMP accumulation by enzyme fragment complementation assay	[PMID: 20329799]
HEK293	EC₅₀	0.04 nM Compound: alpha-MSH	Agonist activity at mouse melanocortin receptor 1 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP AlphaScreen assay Agonist activity at mouse melanocortin receptor 1 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP AlphaScreen assay	[PMID: 32184956]
HEK293	EC₅₀	0.14 nM Compound: alpha-MSH	Agonist activity at mouse melanocortin 1 receptor expressed in HEK293 cells by AlphaScreen cAMP assay Agonist activity at mouse melanocortin 1 receptor expressed in HEK293 cells by AlphaScreen cAMP assay	[PMID: 26433448]
HEK293	EC₅₀	0.15 nM Compound: alpha-MSH	Agonist activity at mouse MC1R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assay Agonist activity at mouse MC1R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assay	[PMID: 26959173]
HEK293	EC₅₀	0.22 nM Compound: alpha-MSH	Agonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP Alpha-screen assay Agonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP Alpha-screen assay	[PMID: 32184956]
HEK293	EC₅₀	0.22 nM Compound: alpha-MSH	Agonist activity at mouse melanocortin receptor 5 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP Alpha-screen assay Agonist activity at mouse melanocortin receptor 5 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP Alpha-screen assay	[PMID: 32184956]
HEK293	EC₅₀	0.22 nM Compound: alpha-MSH	Agonist activity at mouse MC5 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assay Agonist activity at mouse MC5 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assay	[PMID: 26005535]
HEK293	EC₅₀	0.28 nM Compound: alpha-MSH	Agonist activity at mouse MC1R expressed in HEK293 cells by beta-galactosidase assay Agonist activity at mouse MC1R expressed in HEK293 cells by beta-galactosidase assay	[PMID: 15615519]
HEK293	EC₅₀	0.3 nM Compound: alpha-MSH	Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assay Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assay	[PMID: 26005535]
HEK293	EC₅₀	0.36 μM Compound: alpha-MSH	Agonist activity at human recombinant MC5 receptor expressed in HEK293 cells assessed as cAMP accumulation by beta lactamase reporter gene assay Agonist activity at human recombinant MC5 receptor expressed in HEK293 cells assessed as cAMP accumulation by beta lactamase reporter gene assay	[PMID: 20329799]
HEK293	EC₅₀	0.4 nM Compound: alpha-MSH	Agonist activity at mouse MC3 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assay Agonist activity at mouse MC3 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assay	[PMID: 26005535]
HEK293	EC₅₀	0.5 nM Compound: alpha-MSH	Agonist activity at mouse melanocortin 3 receptor expressed in HEK293 cells by AlphaScreen cAMP assay Agonist activity at mouse melanocortin 3 receptor expressed in HEK293 cells by AlphaScreen cAMP assay	[PMID: 26433448]
HEK293	EC₅₀	0.51 nM Compound: alpha-MSH	Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells by AlphaScreen cAMP assay Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells by AlphaScreen cAMP assay	[PMID: 26433448]
HEK293	EC₅₀	0.52 nM Compound: alpha-MSH	Agonist activity at mouse MC3R expressed in HEK293 cells by beta-galactosidase assay Agonist activity at mouse MC3R expressed in HEK293 cells by beta-galactosidase assay	[PMID: 15615519]
HEK293	EC₅₀	0.59 nM Compound: alpha-MSH	Agonist activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assay Agonist activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assay	[PMID: 26959173]
HEK293	EC₅₀	0.65 nM Compound: alpha-MSH	Agonist activity at wild type human melanocortin-4 receptor expressed in HEK293 cells co-transfected with CRE/beta-galactosidase reporter gene assessed as stimulatory response after 6 hrs Agonist activity at wild type human melanocortin-4 receptor expressed in HEK293 cells co-transfected with CRE/beta-galactosidase reporter gene assessed as stimulatory response after 6 hrs	[PMID: 24517312]
HEK293	EC₅₀	0.7 nM Compound: alpha-MSH	Agonist activity at mouse MC1R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay Agonist activity at mouse MC1R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay	[PMID: 18271518]
HEK293	EC₅₀	0.76 nM Compound: alpha-MSH	Agonist activity at mouse MC3R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assay Agonist activity at mouse MC3R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assay	[PMID: 26959173]
HEK293	EC₅₀	1.12 nM Compound: alpha-MSH	Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assay Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase assay	[PMID: 15615519]
HEK293	EC₅₀	1.7 nM Compound: alpha-MSH	Agonist activity at mouse MC4 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assay Agonist activity at mouse MC4 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assay	[PMID: 26005535]
HEK293	EC₅₀	1.8 nM Compound: alpha-MSH	Agonist activity at the mutant MC4R F184A expressed in HEK293 cells by cAMP accumulation Agonist activity at the mutant MC4R F184A expressed in HEK293 cells by cAMP accumulation	[PMID: 16451057]
HEK293	EC₅₀	1.89 nM Compound: alpha-MSH	Agonist activity at mouse MC4R expressed in HEK293 cells by beta-galactosidase assay Agonist activity at mouse MC4R expressed in HEK293 cells by beta-galactosidase assay	[PMID: 15615519]
HEK293	EC₅₀	156 nM Compound: alpha-MSH	Agonist activity at the mutant MC4R Y287A expressed in HEK293 cells by cAMP accumulation Agonist activity at the mutant MC4R Y287A expressed in HEK293 cells by cAMP accumulation	[PMID: 16451057]
HEK293	EC₅₀	16.7 nM Compound: alpha-MSH	Agonist activity at EYFP-fused human MC3R expressed in HEK293 cells after 16 to 20 hrs by CRE-driven reporter assay Agonist activity at EYFP-fused human MC3R expressed in HEK293 cells after 16 to 20 hrs by CRE-driven reporter assay	[PMID: 28972753]
HEK293	EC₅₀	18 nM Compound: alpha-MSH	Agonist activity at the mutant MC4R F184L expressed in HEK293 cells by cAMP accumulation Agonist activity at the mutant MC4R F184L expressed in HEK293 cells by cAMP accumulation	[PMID: 16451057]
HEK293	EC₅₀	2 nM Compound: alpha-MSH	Agonist activity at mouse MC5R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay Agonist activity at mouse MC5R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay	[PMID: 18271518]
HEK293	EC₅₀	2.14 nM Compound: alpha-MSH	Agonist activity at mouse MC3R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay Agonist activity at mouse MC3R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay	[PMID: 18271518]
HEK293	EC₅₀	2.56 nM Compound: alpha-MSH	Agonist activity at mouse MC4R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay Agonist activity at mouse MC4R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay	[PMID: 18271518]
HEK293	EC₅₀	2.6 nM Compound: alpha-MSH	Agonist activity at the mutant MC4R Y287F expressed in HEK293 cells by cAMP accumulation Agonist activity at the mutant MC4R Y287F expressed in HEK293 cells by cAMP accumulation	[PMID: 16451057]
HEK293	EC₅₀	2.9 nM Compound: alpha-MSH	Agonist activity at mouse melanocortin 4 receptor expressed in HEK293 cells by AlphaScreen cAMP assay Agonist activity at mouse melanocortin 4 receptor expressed in HEK293 cells by AlphaScreen cAMP assay	[PMID: 26433448]
HEK293	EC₅₀	2.9 nM Compound: alpha-MSH	Agonist activity at the human wild type MC4R expressed in HEK293 cells by cAMP accumulation Agonist activity at the human wild type MC4R expressed in HEK293 cells by cAMP accumulation	[PMID: 16451057]
HEK293	EC₅₀	21 nM Compound: alpha-MSH	Agonist activity at the mutant MC4R Y268A expressed in HEK293 cells by cAMP accumulation Agonist activity at the mutant MC4R Y268A expressed in HEK293 cells by cAMP accumulation	[PMID: 16451057]
HEK293	EC₅₀	21 nM Compound: alpha-MSH	Agonist activity at the mutant MC4R I125A expressed in HEK293 cells by cAMP accumulation Agonist activity at the mutant MC4R I125A expressed in HEK293 cells by cAMP accumulation	[PMID: 16451057]
HEK293	EC₅₀	24.4 nM Compound: alpha-MSH	Agonist activity at EYFP-fused human MC4R expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by luminescent enzymatic complementation based assay Agonist activity at EYFP-fused human MC4R expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by luminescent enzymatic complementation based assay	[PMID: 28972753]
HEK293	EC₅₀	27 nM Compound: alpha-MSH	Agonist activity at the mutant MC4R I129A expressed in HEK293 cells by cAMP accumulation Agonist activity at the mutant MC4R I129A expressed in HEK293 cells by cAMP accumulation	[PMID: 16451057]
HEK293	EC₅₀	3.7 nM Compound: alpha-MSH	Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP Alpha-screen assay Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP Alpha-screen assay	[PMID: 32184956]
HEK293	EC₅₀	35.3 nM Compound: alpha-MSH	Agonist activity at EYFP-fused human MC5R expressed in HEK293 cells after 16 to 20 hrs by CRE-driven reporter assay Agonist activity at EYFP-fused human MC5R expressed in HEK293 cells after 16 to 20 hrs by CRE-driven reporter assay	[PMID: 28972753]
HEK293	EC₅₀	4 nM Compound: alpha-MSH	Agonist activity at mouse MC4R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assay Agonist activity at mouse MC4R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assay	[PMID: 26959173]
HEK293	EC₅₀	7.1 nM Compound: alpha-MSH	Agonist activity at the mutant MC4R Y268F expressed in HEK293 cells by cAMP accumulation Agonist activity at the mutant MC4R Y268F expressed in HEK293 cells by cAMP accumulation	[PMID: 16451057]
HEK293	EC₅₀	89 nM Compound: alpha-MSH	Agonist activity at the mutant MC4R I291A expressed in HEK293 cells by cAMP accumulation Agonist activity at the mutant MC4R I291A expressed in HEK293 cells by cAMP accumulation	[PMID: 16451057]
HEK293	EC₅₀	9.2 nM Compound: alpha-MSH	Agonist activity at EYFP-fused human MC4R expressed in HEK293 cells after 16 to 20 hrs by CRE-driven reporter assay Agonist activity at EYFP-fused human MC4R expressed in HEK293 cells after 16 to 20 hrs by CRE-driven reporter assay	[PMID: 28972753]
SAOS-2	EC₅₀	1.8 nM Compound: alpha-MSH	Activity at human MC1R by cAMP accumulation in SaoS2 cells Activity at human MC1R by cAMP accumulation in SaoS2 cells	[PMID: 16678415]
SAOS-2	EC₅₀	72.9 nM Compound: alpha-MSH	Activity at human MC4R by cAMP accumulation in SaoS2 cells Activity at human MC4R by cAMP accumulation in SaoS2 cells	[PMID: 16678415]

In Vitro

α-MSH modulates CNS inflammation by acting directly on melanocortin receptors in glial cells. α-MSH modulates NFκB activation. α-MSH inhibits translocation of transcription factor κB to the nucleus^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

α-MSH (50 μg/0.2 ml saline; i.p.) given systemically effectively modulates inflammatory reactions^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	IL-10–deficient mice^[3]
Dosage:	50 µg/0.2 ml saline
Administration:	I.p.
Result:	Given systemically effectively modulated inflammatory reactions.

Molecular Weight

1664.88

Formula

C₇₇H₁₀₉N₂₁O₁₉S

CAS No.

581-05-5

Appearance

Solid

Color

White to off-white

Sequence

Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

Sequence Shortening

Ac-SYSMEHFRWGKPV-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (60.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : ≥ 12.5 mg/mL (7.51 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.6006 mL	3.0032 mL	6.0064 mL
5 mM	0.1201 mL	0.6006 mL	1.2013 mL
10 mM	0.0601 mL	0.3003 mL	0.6006 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.57%

Select Batch:

Data Sheet (277 KB) SDS (252 KB)

COA (251 KB) RP-HPLC (223 KB) Elemental Analysis Report (110 KB)

Handling Instructions (2659 KB)

References

[1]. Madhuri Singh, et al. C-terminal amino acids of alpha-melanocyte-stimulating hormone are requisite for its antibacterial activity against Staphylococcus aureus. Antimicrob Agents Chemother. 2011 May;55(5):1920-9. [Content Brief]

[2]. M S Kim, et al. Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone. Diabetes. 2000 Feb;49(2):177-82. [Content Brief]

[3]. Lipton JM, et al. Mechanisms of antiinflammatory action of alpha-MSH peptides. In vivo and in vitro evidence. Ann N Y Acad Sci. 1999;885:173-182. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	0.6006 mL	3.0032 mL	6.0064 mL	15.0161 mL
H₂O / DMSO	5 mM	0.1201 mL	0.6006 mL	1.2013 mL	3.0032 mL
DMSO	10 mM	0.0601 mL	0.3003 mL	0.6006 mL	1.5016 mL
	15 mM	0.0400 mL	0.2002 mL	0.4004 mL	1.0011 mL
	20 mM	0.0300 mL	0.1502 mL	0.3003 mL	0.7508 mL
	25 mM	0.0240 mL	0.1201 mL	0.2403 mL	0.6006 mL
	30 mM	0.0200 mL	0.1001 mL	0.2002 mL	0.5005 mL
	40 mM	0.0150 mL	0.0751 mL	0.1502 mL	0.3754 mL
	50 mM	0.0120 mL	0.0601 mL	0.1201 mL	0.3003 mL
	60 mM	0.0100 mL	0.0501 mL	0.1001 mL	0.2503 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

α-MSH Related Classifications

Neurological Disease Metabolic Disease Inflammation/Immunology

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-MSH581-05-5α-Melanocyte-Stimulating HormoneMelanocortin ReceptorMC Receptoralpha-melanocyte-stimulatinghormoneendogenousanti-inflammatoryneuroimmunomodulatorypeptideinflammationInhibitorinhibitorinhibit

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α-MSH (Synonyms: α-Melanocyte-Stimulating Hormone)

Customer Review

Other Forms of α-MSH:

α-MSH Related Antibodies

14 Publications Citing Use of MCE α-MSH

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•Related Screening Libraries:

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•Related Proteins:

View All Melanocortin Receptor Isoform Specific Products:

Biological Activity

Purity & Documentation

References

Customer Review

α-MSH Related Antibodies

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

α-MSH Related Classifications

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