2. GPCR/G Protein
  3. Adenosine Receptor
  4. A3AR antagonist 5

A3AR antagonist 5 (Compound 16) is a selective antagonist for human adenosine A3 receptor with an affinity pC of 4.542 μM.

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A3AR antagonist 5 Chemical Structure

A3AR antagonist 5 Chemical Structure

CAS No. : 333436-43-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 33 In-stock
Solution
10 mM * 1 mL in DMSO USD 33 In-stock
Solid
5 mg USD 30 In-stock
10 mg USD 45 In-stock
25 mg USD 80 In-stock
50 mg USD 125 In-stock
100 mg USD 200 In-stock
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A3AR antagonist 5 Related Antibodies

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Adenosine A1 receptor (A1R) Adenosine A2A receptor (A2AR) Adenosine A2B receptor (A2BR) Adenosine A3 receptor (A3R)

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Description

A3AR antagonist 5 (Compound 16) is a selective antagonist for human adenosine A3 receptor with an affinity pC of 4.542 μM[1].

Molecular Weight

324.40

Formula

C18H16N2O2S
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(CC1=CC=CC=C1)NC2=NC(C3=CC=C(OC)C=C3)=CS2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (385.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0826 mL 15.4131 mL 30.8261 mL
5 mM 0.6165 mL 3.0826 mL 6.1652 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0826 mL 15.4131 mL 30.8261 mL 77.0654 mL
5 mM 0.6165 mL 3.0826 mL 6.1652 mL 15.4131 mL
10 mM 0.3083 mL 1.5413 mL 3.0826 mL 7.7065 mL
15 mM 0.2055 mL 1.0275 mL 2.0551 mL 5.1377 mL
20 mM 0.1541 mL 0.7707 mL 1.5413 mL 3.8533 mL
25 mM 0.1233 mL 0.6165 mL 1.2330 mL 3.0826 mL
30 mM 0.1028 mL 0.5138 mL 1.0275 mL 2.5688 mL
40 mM 0.0771 mL 0.3853 mL 0.7707 mL 1.9266 mL
50 mM 0.0617 mL 0.3083 mL 0.6165 mL 1.5413 mL
60 mM 0.0514 mL 0.2569 mL 0.5138 mL 1.2844 mL
80 mM 0.0385 mL 0.1927 mL 0.3853 mL 0.9633 mL
100 mM 0.0308 mL 0.1541 mL 0.3083 mL 0.7707 mL
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A3AR antagonist 5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A3AR antagonist 5333436-43-4Adenosine ReceptorP1 receptorCHOselectiveInhibitorinhibitorinhibit

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