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AA41612 is a potent antagonist of melanopsin-mediated phototransduction.

For research use only. We do not sell to patients.

AA41612 Chemical Structure

AA41612 Chemical Structure

CAS No. : 433690-62-1

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Description

AA41612 is a potent antagonist of melanopsin-mediated phototransduction[1].

Molecular Weight

324.22

Formula

C12H15Cl2NO3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(N1CCCCC1)(C2=CC(Cl)=C(OC)C=C2Cl)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (771.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0843 mL 15.4216 mL 30.8433 mL
5 mM 0.6169 mL 3.0843 mL 6.1687 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.78%

SDS (251 KB)

COA (252 KB) HNMR (247 KB) LCMS (97 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0843 mL 15.4216 mL 30.8433 mL 77.1081 mL
5 mM 0.6169 mL 3.0843 mL 6.1687 mL 15.4216 mL
10 mM 0.3084 mL 1.5422 mL 3.0843 mL 7.7108 mL
15 mM 0.2056 mL 1.0281 mL 2.0562 mL 5.1405 mL
20 mM 0.1542 mL 0.7711 mL 1.5422 mL 3.8554 mL
25 mM 0.1234 mL 0.6169 mL 1.2337 mL 3.0843 mL
30 mM 0.1028 mL 0.5141 mL 1.0281 mL 2.5703 mL
40 mM 0.0771 mL 0.3855 mL 0.7711 mL 1.9277 mL
50 mM 0.0617 mL 0.3084 mL 0.6169 mL 1.5422 mL
60 mM 0.0514 mL 0.2570 mL 0.5141 mL 1.2851 mL
80 mM 0.0386 mL 0.1928 mL 0.3855 mL 0.9639 mL
100 mM 0.0308 mL 0.1542 mL 0.3084 mL 0.7711 mL
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AA41612 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AA41612433690-62-1AA 41612AA-41612OthersInhibitorinhibitorinhibit

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