2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. Abiraterone sulfate

Abiraterone sulfate is a metabolite of Abiraterone (HY-148377). Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity.

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Abiraterone sulfate Chemical Structure

Abiraterone sulfate Chemical Structure

CAS No. : 1993430-25-3

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1 mg USD 130 In-stock
5 mg USD 320 In-stock
10 mg USD 520 In-stock
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Abiraterone sulfate Related Antibodies

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Description

Abiraterone sulfate is a metabolite of Abiraterone (HY-148377). Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity[1].

Molecular Weight

429.57

Formula

C24H31NO4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC=C2C3=CN=CC=C3)([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)OS(=O)(O)=O)=CC4)C)([H])CC1
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (29.10 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3279 mL 11.6395 mL 23.2791 mL
5 mM 0.4656 mL 2.3279 mL 4.6558 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3279 mL 11.6395 mL 23.2791 mL 58.1977 mL
5 mM 0.4656 mL 2.3279 mL 4.6558 mL 11.6395 mL
10 mM 0.2328 mL 1.1640 mL 2.3279 mL 5.8198 mL
15 mM 0.1552 mL 0.7760 mL 1.5519 mL 3.8798 mL
20 mM 0.1164 mL 0.5820 mL 1.1640 mL 2.9099 mL
25 mM 0.0931 mL 0.4656 mL 0.9312 mL 2.3279 mL
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Abiraterone sulfate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Abiraterone1993430-25-3Drug MetaboliteInhibitorinhibitorinhibit

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