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  6. Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp

Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp 

Cat. No.: HY-P10461 Purity: 99.65%
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Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1), and can be used for detection of proteinase 3 (PR3) activity.

For research use only. We do not sell to patients.

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Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp Chemical Structure

Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp Chemical Structure

CAS No. : 1042405-14-0

Size Price Stock Quantity
5 mg USD 300 In-stock
10 mg USD 450 In-stock
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100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp Related Antibodies

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Description

Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1), and can be used for detection of proteinase 3 (PR3) activity[1][2].

Molecular Weight

1285.33

Formula

C53H80N20O18
CAS No.
Appearance

Solid

Color

White to yellow

Sequence

{Abz}-Val-Ala-Asp-{Nva}-Arg-Asp-Arg-Gln-{EDDnp}
Sequence Shortening

{Abz}-VAD-{Nva}-RDDQ-{EDDnp}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (77.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7780 mL 3.8901 mL 7.7801 mL
5 mM 0.1556 mL 0.7780 mL 1.5560 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7780 mL 3.8901 mL 7.7801 mL 19.4503 mL
5 mM 0.1556 mL 0.7780 mL 1.5560 mL 3.8901 mL
10 mM 0.0778 mL 0.3890 mL 0.7780 mL 1.9450 mL
15 mM 0.0519 mL 0.2593 mL 0.5187 mL 1.2967 mL
20 mM 0.0389 mL 0.1945 mL 0.3890 mL 0.9725 mL
25 mM 0.0311 mL 0.1556 mL 0.3112 mL 0.7780 mL
30 mM 0.0259 mL 0.1297 mL 0.2593 mL 0.6483 mL
40 mM 0.0195 mL 0.0973 mL 0.1945 mL 0.4863 mL
50 mM 0.0156 mL 0.0778 mL 0.1556 mL 0.3890 mL
60 mM 0.0130 mL 0.0648 mL 0.1297 mL 0.3242 mL
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Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp1042405-14-0OthersPR3 substrateInhibitorinhibitorinhibit

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