Ac-Arg-Gly-Lys(Ac)-AMC

Name: Ac-Arg-Gly-Lys(Ac)-AMC
Brand: MedChemExpress
SKU: HY-P2462
Rating: 4.5 (1 reviews)

Cat. No.: HY-P2462 Purity: 99.27%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Ac-Arg-Gly-Lys(Ac)-AMC is a substrate for HDAC.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ac-Arg-Gly-Lys(Ac)-AMC Chemical Structure

CAS No. : 660846-97-9

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All HDAC Isoform Specific Products:

View All Isoforms

HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

Biological Activity
Purity & Documentation
References
Customer Review

Description

Ac-Arg-Gly-Lys(Ac)-AMC is a substrate for HDAC^[1].

In Vitro

Following initial inhibition of HDACs, the peptide substrate Ac-Arg-Gly-Lys-AMC is added to the reaction tubes for next 30?min and finally the stop solution stopped the reaction mediated by HDAC enzymes^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

600.67

Formula

C₂₈H₄₀N₈O₇

CAS No.

660846-97-9

Appearance

Solid

Color

White to off-white

Sequence Shortening

Ac-RG{K(Ac)}-AMC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility

In Vitro:

H₂O : ≥ 50 mg/mL (83.24 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6648 mL	8.3240 mL	16.6481 mL
5 mM	0.3330 mL	1.6648 mL	3.3296 mL
10 mM	0.1665 mL	0.8324 mL	1.6648 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.27%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (248 KB) RP-HPLC (107 KB) MS (189 KB) Elemental Analysis Report (108 KB)

Handling Instructions (2659 KB)

References

[1]. Meike Kespohl, et al. The Microbial Metabolite Butyrate Induces Expression of Th1-Associated Factors in CD4 + T Cells Front Immunol. 2017 Aug 28;8:1036. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.6648 mL	8.3240 mL	16.6481 mL	41.6202 mL
	5 mM	0.3330 mL	1.6648 mL	3.3296 mL	8.3240 mL
	10 mM	0.1665 mL	0.8324 mL	1.6648 mL	4.1620 mL
	15 mM	0.1110 mL	0.5549 mL	1.1099 mL	2.7747 mL
	20 mM	0.0832 mL	0.4162 mL	0.8324 mL	2.0810 mL
	25 mM	0.0666 mL	0.3330 mL	0.6659 mL	1.6648 mL
	30 mM	0.0555 mL	0.2775 mL	0.5549 mL	1.3873 mL
	40 mM	0.0416 mL	0.2081 mL	0.4162 mL	1.0405 mL
	50 mM	0.0333 mL	0.1665 mL	0.3330 mL	0.8324 mL
	60 mM	0.0277 mL	0.1387 mL	0.2775 mL	0.6937 mL
	80 mM	0.0208 mL	0.1041 mL	0.2081 mL	0.5203 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.