2. Apoptosis
  3. Caspase
  4. Ac-Tyr-Val-Lys-Asp-aldehyde

Ac-Tyr-Val-Lys-Asp-aldehyde is a caspase-1 inhibitor, can be used for disease research including anemia-associated to chronic diseases, chemotherapy-induced anemia and Diamond-Blackfan anemia.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ac-Tyr-Val-Lys-Asp-aldehyde Chemical Structure

Ac-Tyr-Val-Lys-Asp-aldehyde Chemical Structure

CAS No. : 147821-01-0

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Based on 1 publication(s) in Google Scholar

Ac-Tyr-Val-Lys-Asp-aldehyde Related Antibodies

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Description

Ac-Tyr-Val-Lys-Asp-aldehyde is a caspase-1 inhibitor, can be used for disease research including anemia-associated to chronic diseases, chemotherapy-induced anemia and Diamond-Blackfan anemia[1].

IC50 & Target[1]

Caspase-1

 

Molecular Weight

549.62

Formula

C26H39N5O8
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

{Ac}-YVKD-CHO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (113.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8194 mL 9.0972 mL 18.1944 mL
5 mM 0.3639 mL 1.8194 mL 3.6389 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8194 mL 9.0972 mL 18.1944 mL 45.4860 mL
5 mM 0.3639 mL 1.8194 mL 3.6389 mL 9.0972 mL
10 mM 0.1819 mL 0.9097 mL 1.8194 mL 4.5486 mL
15 mM 0.1213 mL 0.6065 mL 1.2130 mL 3.0324 mL
20 mM 0.0910 mL 0.4549 mL 0.9097 mL 2.2743 mL
25 mM 0.0728 mL 0.3639 mL 0.7278 mL 1.8194 mL
30 mM 0.0606 mL 0.3032 mL 0.6065 mL 1.5162 mL
40 mM 0.0455 mL 0.2274 mL 0.4549 mL 1.1371 mL
50 mM 0.0364 mL 0.1819 mL 0.3639 mL 0.9097 mL
60 mM 0.0303 mL 0.1516 mL 0.3032 mL 0.7581 mL
80 mM 0.0227 mL 0.1137 mL 0.2274 mL 0.5686 mL
100 mM 0.0182 mL 0.0910 mL 0.1819 mL 0.4549 mL
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Ac-Tyr-Val-Lys-Asp-aldehyde Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac-Tyr-Val-Lys-Asp-aldehyde147821-01-0Caspaseanemia-associated to chronic diseaseschemotherapy-induced anemia and Diamond-Blackfan anemiaInhibitorinhibitorinhibit

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