2. GPCR/G Protein
  3. Formyl Peptide Receptor (FPR)
  4. Ac9-25

Ac9-25, a N-terminal peptide of Annexin I, acts as a formyl peptide receptor (FPR) agonist and activates the neutrophil NADPH oxidase through FPR.

For research use only. We do not sell to patients.

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Ac9-25 Chemical Structure

Ac9-25 Chemical Structure

CAS No. : 284040-76-2

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Based on 1 publication(s) in Google Scholar

Other Forms of Ac9-25:

Ac9-25 Related Antibodies

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Description

Ac9-25, a N-terminal peptide of Annexin I, acts as a formyl peptide receptor (FPR) agonist and activates the neutrophil NADPH oxidase through FPR[1][2].

Molecular Weight

2183.33

Formula

C99H143N23O33
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ac-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys
Sequence Shortening

Ac-QAWFIENEEQEYVQTVK
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (22.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4580 mL 2.2901 mL 4.5802 mL
5 mM 0.0916 mL 0.4580 mL 0.9160 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.4580 mL 2.2901 mL 4.5802 mL 11.4504 mL
5 mM 0.0916 mL 0.4580 mL 0.9160 mL 2.2901 mL
10 mM 0.0458 mL 0.2290 mL 0.4580 mL 1.1450 mL
15 mM 0.0305 mL 0.1527 mL 0.3053 mL 0.7634 mL
20 mM 0.0229 mL 0.1145 mL 0.2290 mL 0.5725 mL
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Ac9-25 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac9-25284040-76-2Formyl Peptide Receptor (FPR)peptideneutrophilextravasationNADPH-oxidasesuperoxideanionsInhibitorinhibitorinhibit

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