2. Neuronal Signaling
  3. Amyloid-β Cholinesterase (ChE)
  4. AChE/Aβ-IN-5

AChE/Aβ-IN-5 (compound AV-2) is a bifunctional inhibitor that targets AChE and auto-induced Aβ (Amyloid-β) aggregation. AChE/Aβ-IN-5 can significantly improve scopolamine- and Aβ-induced cognitive impairment in mice.

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AChE/Aβ-IN-5 Chemical Structure

AChE/Aβ-IN-5 Chemical Structure

CAS No. : 181114-32-9

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AChE/Aβ-IN-5 Related Antibodies

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Description

AChE/Aβ-IN-5 (compound AV-2) is a bifunctional inhibitor that targets AChE and auto-induced Aβ (Amyloid-β) aggregation. AChE/Aβ-IN-5 can significantly improve scopolamine- and Aβ-induced cognitive impairment in mice[1].

IC50 & Target

AChE[1]
Molecular Weight

380.48

Formula

C25H24N4
CAS No.
SMILES

C1(C2=CC=CC=C2)=NC(N3CCN(CC3)CC4=CC=CC=C4)=C5C=CC=CC5=N1
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Purity & Documentation
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AChE/Aβ-IN-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AChE/Aβ-IN-5181114-32-9Amyloid-βCholinesterase (ChE)β-amyloid peptideAβAbetaY mazeMorris water mazecognitive impairmentInhibitorinhibitorinhibit

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