2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. AChE-IN-23

AChE-IN-23 (compound 3h) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 48.3 μM.

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AChE-IN-23 Chemical Structure

AChE-IN-23 Chemical Structure

CAS No. : 6297-14-9

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Based on 1 publication(s) in Google Scholar

AChE-IN-23 Related Antibodies

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Description

AChE-IN-23 (compound 3h) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 48.3 μM[1].

Molecular Weight

267.20

Formula

C11H20Cl2N2O
CAS No.
Appearance

Solid

Color

Off-white to gray

SMILES

OC1=CC=C(N)C=C1CN(CC)CC.[H]Cl.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (374.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7425 mL 18.7126 mL 37.4251 mL
5 mM 0.7485 mL 3.7425 mL 7.4850 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.49%

COA (248 KB) HNMR (267 KB) LCMS (86 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7425 mL 18.7126 mL 37.4251 mL 93.5629 mL
5 mM 0.7485 mL 3.7425 mL 7.4850 mL 18.7126 mL
10 mM 0.3743 mL 1.8713 mL 3.7425 mL 9.3563 mL
15 mM 0.2495 mL 1.2475 mL 2.4950 mL 6.2375 mL
20 mM 0.1871 mL 0.9356 mL 1.8713 mL 4.6781 mL
25 mM 0.1497 mL 0.7485 mL 1.4970 mL 3.7425 mL
30 mM 0.1248 mL 0.6238 mL 1.2475 mL 3.1188 mL
40 mM 0.0936 mL 0.4678 mL 0.9356 mL 2.3391 mL
50 mM 0.0749 mL 0.3743 mL 0.7485 mL 1.8713 mL
60 mM 0.0624 mL 0.3119 mL 0.6238 mL 1.5594 mL
80 mM 0.0468 mL 0.2339 mL 0.4678 mL 1.1695 mL
100 mM 0.0374 mL 0.1871 mL 0.3743 mL 0.9356 mL
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AChE-IN-23 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AChE-IN-236297-14-9Cholinesterase (ChE)acetylcholinesteraseAChEInhibitorinhibitorinhibit

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