2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. AChE-IN-47

AChE-IN-47 (compound g17) is a AChE inhibitor with the IC50 of 0.24 μM. AChE-IN-47 inhibits amyloid β peptides self-aggregation. AChE-IN-47 displays neuroprotective effects and effectively suppresses the intracellular accumulation of reactive oxygen species.

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AChE-IN-47 Chemical Structure

AChE-IN-47 Chemical Structure

CAS No. : 3033056-55-9

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AChE-IN-47 Related Antibodies

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Description

AChE-IN-47 (compound g17) is a AChE inhibitor with the IC50 of 0.24 μM. AChE-IN-47 inhibits amyloid β peptides self-aggregation. AChE-IN-47 displays neuroprotective effects and effectively suppresses the intracellular accumulation of reactive oxygen species[1].

IC50 & Target

AChE

 

Molecular Weight

466.43

Formula

C20H17F3N4O4S
CAS No.
SMILES

O=C(NC1=CC=C2C(N3CCCC3=NC2=C1)=O)CNS(=O)(C4=CC=CC=C4C(F)(F)F)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AChE-IN-47 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AChE-IN-473033056-55-9Cholinesterase (ChE)neuroprotectiveAlzheimer's diseasereactive oxygen species,Inhibitorinhibitorinhibit

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