1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. AChE-IN-52

AChE-IN-52 (compound A6) is an acetylcholinesterase (AChE) inhibitor. AChE-IN-52 shows antitumor efficacy, especially against breast cancer MCF-7 cells. AChE-IN-52 significantly disrupts the amino acid metabolism and inhibits migration of MCF-7. AChE-IN-52 plays anticancer role by regulating Best1 and HIST1H2BJ.

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AChE-IN-52 Chemical Structure

AChE-IN-52 Chemical Structure

CAS No. : 2214210-63-4

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Description

AChE-IN-52 (compound A6) is an acetylcholinesterase (AChE) inhibitor. AChE-IN-52 shows antitumor efficacy, especially against breast cancer MCF-7 cells. AChE-IN-52 significantly disrupts the amino acid metabolism and inhibits migration of MCF-7. AChE-IN-52 plays anticancer role by regulating Best1 and HIST1H2BJ[1].

IC50 & Target

AChE

 

Molecular Weight

421.56

Formula

C24H27N3O2S

CAS No.
SMILES

O=C(C1=CSC(C2=CC=C(OCC3=CC=CC=C3)C=C2)=N1)NCCN4CCCCC4

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Room temperature in continental US; may vary elsewhere.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
AChE-IN-52
Cat. No.:
HY-163126
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