1. Neuronal Signaling
  2. Cholinesterase (ChE) Monoamine Oxidase
  3. AChE-IN-60

AChE-IN-60 (compound 6k) is a potant acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitor with IC50s of 27 nM and 43 nM, respectively. AChE-IN-60 also inhibits monoamine oxidase (MAO)-A and MAO-B with IC50s of 353 nM and 716 nM, respectively.

For research use only. We do not sell to patients.

AChE-IN-60 Chemical Structure

AChE-IN-60 Chemical Structure

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Description

AChE-IN-60 (compound 6k) is a potant acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitor with IC50s of 27 nM and 43 nM, respectively. AChE-IN-60 also inhibits monoamine oxidase (MAO)-A and MAO-B with IC50s of 353 nM and 716 nM, respectively[1].

IC50 & Target[1]

AChE

27 nM (IC50)

BChE

43 nM (IC50)

MAO-A

353 nM (IC50)

MAO-B

716 nM (IC50)

Molecular Weight

519.70

Formula

C24H29N3O4S3

SMILES

CCCCCCCCOC(C1=CC2=C(N=C(S2)NC(NS(=O)(C3=CC=C(C=C3)C)=O)=S)C=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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AChE-IN-60
Cat. No.:
HY-157981
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