2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. DNA/RNA Synthesis Endogenous Metabolite
  4. Adenine-d

Adenine-d  (Synonyms: 6-Aminopurine-d1; Vitamin B4-d1)

Cat. No.: HY-B0152S Purity: ≥99.0%
COA Handling Instructions

Molarity Calculator

Adenine-d is the deuterium labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[1][2][3].

For research use only. We do not sell to patients.

Adenine-d Chemical Structure

Adenine-d Chemical Structure

CAS No. : 109923-52-6

Size Price Stock Quantity
5 mg USD 200 In-stock
10 mg USD 320 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Adenine-d:

Adenine-d Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Adenine-d is the deuterium labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Adenine-d Related Antibodies
Molecular Weight

136.13

Formula

C5H4DN5
CAS No.
Unlabeled CAS

73-24-5
Appearance

Solid

Color

White to off-white

SMILES

[2H]C1=NC(N)=C2N=CNC2=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

1 M HCL : 20 mg/mL (146.92 mM; Need ultrasonic)

1M HCl : 20 mg/mL (146.92 mM; Need ultrasonic)

DMSO : ≥ 10 mg/mL (73.46 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 10 mg/mL (73.46 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 2 mg/mL (14.69 mM; ultrasonic and warming and heat to 60°C)

H2O : 2 mg/mL (14.69 mM; ultrasonic and warming and heat to 60°C)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.3459 mL 36.7296 mL 73.4592 mL
5 mM 1.4692 mL 7.3459 mL 14.6918 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O / DMSO / DMSO / 1 M HCL / 1M HCl 1 mM 7.3459 mL 36.7296 mL 73.4592 mL 183.6480 mL
5 mM 1.4692 mL 7.3459 mL 14.6918 mL 36.7296 mL
10 mM 0.7346 mL 3.6730 mL 7.3459 mL 18.3648 mL
DMSO / DMSO / 1 M HCL / 1M HCl 15 mM 0.4897 mL 2.4486 mL 4.8973 mL 12.2432 mL
20 mM 0.3673 mL 1.8365 mL 3.6730 mL 9.1824 mL
25 mM 0.2938 mL 1.4692 mL 2.9384 mL 7.3459 mL
30 mM 0.2449 mL 1.2243 mL 2.4486 mL 6.1216 mL
40 mM 0.1836 mL 0.9182 mL 1.8365 mL 4.5912 mL
50 mM 0.1469 mL 0.7346 mL 1.4692 mL 3.6730 mL
60 mM 0.1224 mL 0.6122 mL 1.2243 mL 3.0608 mL
1 M HCL / 1M HCl 80 mM 0.0918 mL 0.4591 mL 0.9182 mL 2.2956 mL
100 mM 0.0735 mL 0.3673 mL 0.7346 mL 1.8365 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Adenine-d Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adenine-d109923-52-66-Aminopurine-d1Vitamin B4-d1DNA/RNA SynthesisEndogenous MetaboliteInhibitorinhibitorinhibit

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