2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Adenosine 5′-diphosphoribose

Adenosine 5′-diphosphoribose  (Synonyms: ADP ribose)

Cat. No.: HY-100973 Purity: 98.21%
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Adenosine 5′-diphosphoribose (ADP ribose) is composed of an adenine base attached to a ribose sugar, which is in turn linked to two phosphate groups. Adenosine 5′-diphosphoribose is a key molecule involved in a variety of cellular processes, particularly in the response to DNA damage and the regulation of gene expression.

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Adenosine 5′-diphosphoribose Chemical Structure

Adenosine 5′-diphosphoribose Chemical Structure

CAS No. : 20762-30-5

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Based on 4 publication(s) in Google Scholar

Other Forms of Adenosine 5′-diphosphoribose:

Adenosine 5′-diphosphoribose Related Antibodies

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Description

Adenosine 5′-diphosphoribose (ADP ribose) is composed of an adenine base attached to a ribose sugar, which is in turn linked to two phosphate groups. Adenosine 5′-diphosphoribose is a key molecule involved in a variety of cellular processes, particularly in the response to DNA damage and the regulation of gene expression[1].

Molecular Weight

559.32

Formula

C15H23N5O14P2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1COP(OP(OC[C@H]([C@H]([C@H](C=O)O)O)O)(O)=O)(O)=O
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 175 mg/mL (312.88 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7879 mL 8.9394 mL 17.8789 mL
5 mM 0.3576 mL 1.7879 mL 3.5758 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7879 mL 8.9394 mL 17.8789 mL 44.6971 mL
5 mM 0.3576 mL 1.7879 mL 3.5758 mL 8.9394 mL
10 mM 0.1788 mL 0.8939 mL 1.7879 mL 4.4697 mL
15 mM 0.1192 mL 0.5960 mL 1.1919 mL 2.9798 mL
20 mM 0.0894 mL 0.4470 mL 0.8939 mL 2.2349 mL
25 mM 0.0715 mL 0.3576 mL 0.7152 mL 1.7879 mL
30 mM 0.0596 mL 0.2980 mL 0.5960 mL 1.4899 mL
40 mM 0.0447 mL 0.2235 mL 0.4470 mL 1.1174 mL
50 mM 0.0358 mL 0.1788 mL 0.3576 mL 0.8939 mL
60 mM 0.0298 mL 0.1490 mL 0.2980 mL 0.7450 mL
80 mM 0.0223 mL 0.1117 mL 0.2235 mL 0.5587 mL
100 mM 0.0179 mL 0.0894 mL 0.1788 mL 0.4470 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Adenosine 5′-diphosphoribose Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adenosine 5′-diphosphoribose20762-30-5ADP riboseEndogenous MetaboliteInhibitorinhibitorinhibit

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