2. Cell Cycle/DNA Damage Autophagy Apoptosis Metabolic Enzyme/Protease
  3. Nucleoside Antimetabolite/Analog Autophagy Apoptosis Endogenous Metabolite
  4. Adenosine-d

Adenosine-d  (Synonyms: Adenine riboside-d1; D-Adenosine-d)

Cat. No.: HY-B0228S Purity: 99.72%
COA Handling Instructions

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Adenosine-d is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[1][2].

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Adenosine-d Chemical Structure

Adenosine-d Chemical Structure

CAS No. : 109923-50-4

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1 mg USD 65 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Adenosine-d:

Adenosine-d Related Antibodies

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Description

Adenosine-d is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Adenosine-d Related Antibodies
Molecular Weight

268.25

Formula

C10H12DN5O4
CAS No.
Unlabeled CAS

58-61-7
Appearance

Solid

Color

White to off-white

SMILES

NC1=C2C(N([C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C=N2)=NC([2H])=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (124.25 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7279 mL 18.6393 mL 37.2787 mL
5 mM 0.7456 mL 3.7279 mL 7.4557 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.72%

COA (252 KB) HNMR (834 KB) RP-HPLC (764 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7279 mL 18.6393 mL 37.2787 mL 93.1966 mL
5 mM 0.7456 mL 3.7279 mL 7.4557 mL 18.6393 mL
10 mM 0.3728 mL 1.8639 mL 3.7279 mL 9.3197 mL
15 mM 0.2485 mL 1.2426 mL 2.4852 mL 6.2131 mL
20 mM 0.1864 mL 0.9320 mL 1.8639 mL 4.6598 mL
25 mM 0.1491 mL 0.7456 mL 1.4911 mL 3.7279 mL
30 mM 0.1243 mL 0.6213 mL 1.2426 mL 3.1066 mL
40 mM 0.0932 mL 0.4660 mL 0.9320 mL 2.3299 mL
50 mM 0.0746 mL 0.3728 mL 0.7456 mL 1.8639 mL
60 mM 0.0621 mL 0.3107 mL 0.6213 mL 1.5533 mL
80 mM 0.0466 mL 0.2330 mL 0.4660 mL 1.1650 mL
100 mM 0.0373 mL 0.1864 mL 0.3728 mL 0.9320 mL
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Adenosine-d Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adenosine-d109923-50-4Adenine riboside-d1D-Adenosine-dNucleoside Antimetabolite/AnalogAutophagyApoptosisEndogenous MetaboliteInhibitorinhibitorinhibit

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