Adezmapimod (Standard) (Synonyms: SB 203580 (Standard); RWJ 64809 (Standard))

Cat. No.: HY-10256R Purity: ≥98%: Handling Instructions Technical Support

Adezmapimod (Standard) is the analytical standard of Adezmapimod. This product is intended for research and analytical applications. Adezmapimod (SB 203580) is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod inhibits LCK, GSK3β and PKBα with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod does not disrupt JNK activity and is an autophagy and mitophagy activator.

For research use only. We do not sell to patients.

Adezmapimod (Standard) Chemical Structure

CAS No. : 152121-47-6

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Description	Adezmapimod (Standard) is the analytical standard of Adezmapimod . This product is intended for research and analytical applications. Adezmapimod (SB 203580) is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod inhibits LCK, GSK3β and PKBα with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod does not disrupt JNK activity and is an autophagy and mitophagy activator.
Molecular Weight	377.43
Formula	C₂₁H₁₆FN₃OS
CAS No.	152121-47-6
SMILES	O=S(C1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1)C
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Adezmapimod (Standard) Related Classifications

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	×		=		×
C1		V1		C2		V2

Keywords:

Adezmapimod (Standard)152121-47-6SB 203580 (Standard)RWJ 64809 (Standard)Organoidp38 MAPKAutophagyMitophagyMitochondrial AutophagyATP-competitiveSAPK2aSAPK2bLCKGSK3βPKBαInhibitorinhibitorinhibit

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Adezmapimod (Standard) (Synonyms: SB 203580 (Standard); RWJ 64809 (Standard))

Product Information

Purity & Documentation

Customer Review

Adezmapimod (Standard) Related Classifications

Molarity Calculator

Dilution Calculator