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  5. Adrenomedullin (rat)

Adrenomedullin (rat) is an effective vasodilator peptide. Adrenomedullin is actively secreted by endothelial cells (EC) and vascular smooth muscle cells (VSMC).

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Adrenomedullin (rat) Chemical Structure

Adrenomedullin (rat) Chemical Structure

CAS No. : 161383-47-7

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500 μg USD 360 In-stock
1 mg USD 600 In-stock
5 mg USD 1500 In-stock
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Based on 1 publication(s) in Google Scholar

Adrenomedullin (rat) Related Antibodies

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Description

Adrenomedullin (rat) is an effective vasodilator peptide. Adrenomedullin is actively secreted by endothelial cells (EC) and vascular smooth muscle cells (VSMC)[1].

Molecular Weight

5729.41

Formula

C242H381N77O75S5
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Tyr-Arg-Gln-Ser-Met-Asn-Gln-Gly-Ser-Arg-Ser-Thr-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Met-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Gly-Met-Ala-Pro-Arg-Asn-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bridge: Cys14-Cys19)
Sequence Shortening

YRQSMNQGSRSTGCRFGTCTMQKLAHQIYQFTDKDKDGMAPRNKISPQGY-NH2 (Disulfide bridge: Cys14-Cys19)
SMILES

OC(C=C1)=CC=C1C[C@@H](C(N)=O)NC(CNC([C@H](CCC(N)=O)NC([C@H]2N(C([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H](CCCCN)NC([C@H](CC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H]3N(C([C@H](C)NC([C@H](CCSC)NC(CNC([C@H](CC(O)=O)NC([C@H](CCCCN)NC([C@H](CC(O)=O)NC([C@H](CCCCN)NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CC4=CC=CC=C4)NC([C@H](CCC(N)=O)NC([C@H](CC5=CC=C(C=C5)O)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(N)=O)NC([C@H](CC6=CNC=N6)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CCC(N)=O)NC([C@H](CCSC)NC([C@H]([C@H](O)C)NC([C@H](CSSC[C@@H]7NC(CNC([C@H]([C@H](O)C)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC(CNC([C@H](CCC(N)=O)NC([C@H](CC(N)=O)NC([C@H](CCSC)NC([C@H](CO)NC([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC8=CC=C(C=C8)O)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H]([C@H](O)C)NC(CNC([C@H](CC9=CC=CC=C9)NC([C@H](CCCNC(N)=N)NC7=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC3)=O)=O)=O)=O)=O)=O)CCC2)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (17.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.1745 mL 0.8727 mL 1.7454 mL
5 mM 0.0349 mL 0.1745 mL 0.3491 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.1745 mL 0.8727 mL 1.7454 mL 4.3635 mL
5 mM 0.0349 mL 0.1745 mL 0.3491 mL 0.8727 mL
10 mM 0.0175 mL 0.0873 mL 0.1745 mL 0.4363 mL
15 mM 0.0116 mL 0.0582 mL 0.1164 mL 0.2909 mL
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Adrenomedullin (rat) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adrenomedullin (rat)161383-47-7OthersInhibitorinhibitorinhibit

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