2. Vitamin D Related/Nuclear Receptor Apoptosis
  3. Progesterone Receptor Apoptosis
  4. AG-205

AG-205 is a progesterone receptor membrane component-1 (PGRMC1) inhibitor with anti-mitotic, anti-migratory and anti-invasive activities. AG-205 increases expression of genes coding enzymes of the cholesterol biosynthetic pathway or of steroidogenesis. AG-205 promotes Apoptosis modified regulation of the cell cycle and reduces cell migration and invasion capacities in ovary and breast cancer cells.

For research use only. We do not sell to patients.

AG-205 Chemical Structure

AG-205 Chemical Structure

CAS No. : 1375078-57-1

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Based on 1 publication(s) in Google Scholar

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AG-205 Related Antibodies

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Description

AG-205 is a progesterone receptor membrane component-1 (PGRMC1) inhibitor with anti-mitotic, anti-migratory and anti-invasive activities. AG-205 increases expression of genes coding enzymes of the cholesterol biosynthetic pathway or of steroidogenesis. AG-205 promotes Apoptosis modified regulation of the cell cycle and reduces cell migration and invasion capacities in ovary and breast cancer cells[1].

Molecular Weight

454.98

Formula

C22H23ClN6OS
CAS No.
SMILES

CC1=CC2=C(C=C1)N([C@]3([H])[C@@]2([H])CN(CC3)C)C(CSC4=NN=NN4C5=CC=C(C=C5)Cl)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AG-205 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AG-2051375078-57-1AG205AG 205Progesterone ReceptorApoptosisNR3C3PGRMC1anti-mitoticanti-migratoryanti-invasivesteroidogenesiscell migration and invasionovary and breast cancer cellsInhibitorinhibitorinhibit

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