2. PI3K/Akt/mTOR
  3. Akt
  4. AKT inhibitor IV

Akt inhibitor-IV (AKTIV) acts as a PI3K-Akt inhibitor at the E isomer (HY-14971), with potent cytotoxicity.

For research use only. We do not sell to patients.

AKT inhibitor IV Chemical Structure

AKT inhibitor IV Chemical Structure

CAS No. : 681281-88-9

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Based on 1 publication(s) in Google Scholar

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AKT inhibitor IV Related Antibodies

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Description

Akt inhibitor-IV (AKTIV) acts as a PI3K-Akt inhibitor at the E isomer (HY-14971), with potent cytotoxicity[1].

In Vitro

(E)-Akt inhibitor-IV (compound 7) exhibits average GI20 of 0.04 μM on four cell lines (MDA-MB468 cells, MDA-MB231 cells, MCF7 cells and 184B5 cells)[1].
(E)-Akt inhibitor-IV shows little effects on the growth of 184B5 non-cancer cells at the average GI20 doses[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AKT inhibitor IV Related Antibodies
Molecular Weight

614.54

Formula

C31H27IN4S
CAS No.
SMILES

CN(/C=C/C1=[N+](C2=CC=CC=C2)C3=CC=C(C4=NC5=CC=CC=C5S4)C=C3N1CC)C6=CC=CC=C6.[I-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AKT inhibitor IV Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AKT inhibitor IV681281-88-9AKTIVAktPKBProtein kinase BInhibitorinhibitorinhibit

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AKT inhibitor IV
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HY-14971A
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