2. GPCR/G Protein
  3. Natriuretic Peptide Receptor (NPR)
  4. Anaritide

Anaritide  (Synonyms: Human atrial natriuretic factor (102–126))

Cat. No.: HY-P10279 Purity: 98.83%
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Anaritide is a synthetic form of atrial natriuretic peptide (ANP) composed of 25 amino acids. Anaritide increases glomerular filtration rate by dilating into and contracting out the bulbar arterioles. Anaritide can be used to study the effects on patients with acute tubular necrosis, particularly in improving dialysis free survival.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Anaritide Chemical Structure

Anaritide Chemical Structure

CAS No. : 95896-08-5

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Based on 1 publication(s) in Google Scholar

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Description

Anaritide is a synthetic form of atrial natriuretic peptide (ANP) composed of 25 amino acids. Anaritide increases glomerular filtration rate by dilating into and contracting out the bulbar arterioles. Anaritide can be used to study the effects on patients with acute tubular necrosis, particularly in improving dialysis free survival[1].

Molecular Weight

2724.02

Formula

C112H175N39O35S3
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfidebridge:Cys4-Cys20)
Sequence Shortening

RSSCFGGRMDRIGAQSGLGCNSFRY (Disulfidebridge:Cys4-Cys20)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (36.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.3671 mL 1.8355 mL 3.6710 mL
5 mM 0.0734 mL 0.3671 mL 0.7342 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.3671 mL 1.8355 mL 3.6710 mL 9.1776 mL
5 mM 0.0734 mL 0.3671 mL 0.7342 mL 1.8355 mL
10 mM 0.0367 mL 0.1836 mL 0.3671 mL 0.9178 mL
15 mM 0.0245 mL 0.1224 mL 0.2447 mL 0.6118 mL
20 mM 0.0184 mL 0.0918 mL 0.1836 mL 0.4589 mL
25 mM 0.0147 mL 0.0734 mL 0.1468 mL 0.3671 mL
30 mM 0.0122 mL 0.0612 mL 0.1224 mL 0.3059 mL
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Anaritide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anaritide95896-08-5Human atrial natriuretic factor (102–126)Natriuretic Peptide Receptor (NPR)Natriuretic Peptide ReceptorNPRNPR-ANPR-BNPR-CAcute Tubular Necrosisrenal functioncardiovascular diseaseglomerular filtration rateInhibitorinhibitorinhibit

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