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And1-IN-1 (compound III) is a potent And1 inhibitor.

For research use only. We do not sell to patients.

And1-IN-1 Chemical Structure

And1-IN-1 Chemical Structure

CAS No. : 2451028-69-4

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5 mg USD 375 In-stock
10 mg USD 570 In-stock
25 mg USD 1140 In-stock
50 mg USD 1720 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

And1-IN-1 (compound III) is a potent And1 inhibitor[1].

IC50 & Target

And1[1]

Molecular Weight

304.96

Formula

C15H11BCl2O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OB1OCC2=CC(/C=C/C3=CC=C(Cl)C(Cl)=C3)=CC=C21

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 120 mg/mL (393.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2791 mL 16.3956 mL 32.7912 mL
5 mM 0.6558 mL 3.2791 mL 6.5582 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2791 mL 16.3956 mL 32.7912 mL 81.9780 mL
5 mM 0.6558 mL 3.2791 mL 6.5582 mL 16.3956 mL
10 mM 0.3279 mL 1.6396 mL 3.2791 mL 8.1978 mL
15 mM 0.2186 mL 1.0930 mL 2.1861 mL 5.4652 mL
20 mM 0.1640 mL 0.8198 mL 1.6396 mL 4.0989 mL
25 mM 0.1312 mL 0.6558 mL 1.3116 mL 3.2791 mL
30 mM 0.1093 mL 0.5465 mL 1.0930 mL 2.7326 mL
40 mM 0.0820 mL 0.4099 mL 0.8198 mL 2.0494 mL
50 mM 0.0656 mL 0.3279 mL 0.6558 mL 1.6396 mL
60 mM 0.0547 mL 0.2733 mL 0.5465 mL 1.3663 mL
80 mM 0.0410 mL 0.2049 mL 0.4099 mL 1.0247 mL
100 mM 0.0328 mL 0.1640 mL 0.3279 mL 0.8198 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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And1-IN-1
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HY-150184
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