Anhydrovinblastine

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Anhydrovinblastine is a monoterpenoid indole alkaloid that can be isolated from Catharanthus roseus leaves.

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Anhydrovinblastine Chemical Structure

CAS No. : 38390-45-3

Size	Stock
5 mg	Get quote	Estimated Time of Arrival: December 31
10 mg	Get quote	Estimated Time of Arrival: December 31
25 mg	Get quote	Estimated Time of Arrival: December 31

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Other Forms of Anhydrovinblastine:

Anhydrovinblastine sulfate Get quote

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Biological Activity
Purity & Documentation
References
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Description

Anhydrovinblastine is a monoterpenoid indole alkaloid that can be isolated from Catharanthus roseus leaves^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	4.53 μM Compound: 14	Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 26522953]
KB	IC₅₀	2.06 μM Compound: 14	Cytotoxicity against human KB cells after 72 hrs by SRB assay Cytotoxicity against human KB cells after 72 hrs by SRB assay	[PMID: 26522953]
Lu1	IC₅₀	5.98 μM Compound: 14	Cytotoxicity against human Lu1 cells after 72 hrs by SRB assay Cytotoxicity against human Lu1 cells after 72 hrs by SRB assay	[PMID: 26522953]
MCF7	IC₅₀	4.63 μM Compound: 14	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 26522953]

Clinical Trial

Molecular Weight

792.96

Formula

C₄₆H₅₆N₄O₈

CAS No.

38390-45-3

SMILES

CC[C@]1([C@H]2OC(C)=O)[C@@]3([H])[C@](C(C4=C5)=CC([C@](C6=C7C8=CC=CC=C8N6)(C[C@](C=C9CC)([H])C[N@@](C9)CC7)C(OC)=O)=C5OC)(CCN3CC=C1)[C@](N4C)([H])[C@@]2(O)C(OC)=O

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. TrevorKidd, et al. Inter-organ transport of secologanin allows assembly of monoterpenoid