2. Immunology/Inflammation
  3. Interleukin Related
  4. Anti-inflammatory agent 42

Anti-inflammatory agent 42 (Compound 10j) is an anti-inflammatory agent. Anti-inflammatory agent 42 shows excellent inhibition on the expression of TNF-α and IL-6 in LPS (HY-D1056)-stimulated macrophages.

For research use only. We do not sell to patients.

Anti-inflammatory agent 42 Chemical Structure

Anti-inflammatory agent 42 Chemical Structure

CAS No. : 877468-30-9

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Based on 1 publication(s) in Google Scholar

Anti-inflammatory agent 42 Related Antibodies

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Description

Anti-inflammatory agent 42 (Compound 10j) is an anti-inflammatory agent. Anti-inflammatory agent 42 shows excellent inhibition on the expression of TNF-α and IL-6 in LPS (HY-D1056)-stimulated macrophages[1].

In Vitro

Anti-inflammatory agent 42 (Compound 10j; 10 μM; 2 h) inhibits LPS-induced TNF-α and IL-6 secretion in RAW 264.7 macrophages[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-inflammatory agent 42 Related Antibodies
Molecular Weight

328.39

Formula

C20H12N2OS
CAS No.
Appearance

Solid

Color

Light yellow to brown

SMILES

O=C1N2C3=CC=CC=C3N=C2S/C1=C\C4=CC=CC5=C4C=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 1.43 mg/mL (4.35 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0452 mL 15.2258 mL 30.4516 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0452 mL 15.2258 mL 30.4516 mL 76.1290 mL
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Anti-inflammatory agent 42 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-inflammatory agent 42877468-30-9Interleukin RelatedILInhibitorinhibitorinhibit

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Anti-inflammatory agent 42
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HY-153579
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