2. Anti-infection Cell Cycle/DNA Damage
  3. Bacterial Fungal Topoisomerase
  4. Antibacterial agent 229

Antibacterial agent 229 (compound 8a) is a potent antibacterial agent. Antibacterial agent 229 shows antibacterial and antifungal abilities. Antibacterial agent 229 disrupts the integrity of the bacterial membrane, intercalates into DNA. Antibacterial agent 229 inhibits topoisomerase IV with an IC50 value of 10.88 µM.

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Antibacterial agent 229 Chemical Structure

Antibacterial agent 229 Chemical Structure

CAS No. : 3049500-54-8

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Antibacterial agent 229 Related Antibodies

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Description

Antibacterial agent 229 (compound 8a) is a potent antibacterial agent. Antibacterial agent 229 shows antibacterial and antifungal abilities. Antibacterial agent 229 disrupts the integrity of the bacterial membrane, intercalates into DNA. Antibacterial agent 229 inhibits topoisomerase IV with an IC50 value of 10.88 µM[1].

IC50 & Target[1]

TOPO IV

10.88 μM (IC50)

In Vitro

Antibacterial agent 229 (compound 8a) shows antibacterial and antifungal abilities with MIC Values of 0.0377, 0.0047, 0.0189, 0.0189, 0.0189, 0.0189, 0.0047 mM for S. aureus ATCC 25923, S. aureus ATCC 29213, E. coli ATCC 25922, P. aeruginosa ATCC 27853, C. albicans ATCC 9002, C. albicans, C. parapsilosis ATCC 22019, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 229 Related Antibodies
Molecular Weight

424.90

Formula

C16H14ClFN6OS2
CAS No.
SMILES

O=C1C(C2=CSC(N)=N2)=CN(C/C(C)=N/NC(N)=S)C3=CC(Cl)=C(F)C=C31
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antibacterial agent 229 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 2293049500-54-8Antibacterial agent229Antibacterial agent-229BacterialFungalTopoisomeraseAntibacterialantifungalStaphylococcus aureusInhibitorinhibitorinhibit

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