Phospho-PKC zeta (Thr560) Antibody (YA2679)

Phospho-PKC zeta (Thr560) Antibody (YA2679) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2679), targeting Phospho-PKC zeta (Thr560), with a predicted molecular weight of 68 kDa (observed band size: 68 kDa). Phospho-PKC zeta (Thr560) Antibody (YA2679) can be used for WB, IHC-P experiment in human, mouse, rat background.

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.

5590

Predicted band size: 68 kDa; Observed band size: 68 kDa

Affinity Chromatography

Non-conjugated

Phosphorylated

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

Q05513

WB: 1/500-1/1000;IHC: 1/50-1/100

WB, IHC-P

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human PKC zeta