2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. Phospholamban Antibody (YA1622)

Phospholamban Antibody (YA1622)

Cat. No.: HY-P81877
Data Sheet SDS COA User Guide for Antibodies Technical Support

Phospholamban Antibody (YA1622) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1622), targeting Phospholamban, with a predicted molecular weight of 6 kDa (observed band size: 12,24 kDa). Phospholamban Antibody (YA1622) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

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Description

Phospholamban Antibody (YA1622) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1622), targeting Phospholamban, with a predicted molecular weight of 6 kDa (observed band size: 12,24 kDa). Phospholamban Antibody (YA1622) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.
Background

The protein encoded by The related gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in The related gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.
Gene ID
SwissProt ID
Synonyms
PLN; PLB; Cardiac phospholamban; PLB
Molecular Weight

Predicted band size: 6 kDa; Observed band size: 12,24 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Unmodified
RRID
Research Field

Signal Transduction
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100;IP: 1/20
Application

WB, IHC-P, IP
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

Recombinant protein of human Phospholamban
Database

Entrez Gene: 5350 Human ; 18821 Mouse ; 64672 Rat

SwissProt: P26678 Human ; P61014 Mouse ; P61016 Rat

OMIM: 609909 Human

Documentation
Data Sheet (234 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

Phospholamban Antibody (YA1622) Related Classifications

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