1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. AChE-IN-74

AChE-IN-74 (Compound 10) is a modulator for cholinesterase. AChE-IN-74 inhibits the proliferation of liver cancer cell Hep3B and SkHep1 with IC50 of 3.6 and 19.9 μM. AChE-IN-74 exhibits a low embryonic toxicity in zebrafish models (10-15 μM).

For research use only. We do not sell to patients.

AChE-IN-74 Chemical Structure

AChE-IN-74 Chemical Structure

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Description

AChE-IN-74 (Compound 10) is a modulator for cholinesterase. AChE-IN-74 inhibits the proliferation of liver cancer cell Hep3B and SkHep1 with IC50 of 3.6 and 19.9 μM. AChE-IN-74 exhibits a low embryonic toxicity in zebrafish models (10-15 μM)[1].

Molecular Weight

480.02

Formula

C26H26ClN3O2S

SMILES

O=C(N1C2=C(C=CC=C2)SC3=CC=C(Cl)C=C13)CN4CCN(CC5=CC=C(OC)C=C5)CC4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
AChE-IN-74
Cat. No.:
HY-162657
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