2. Anti-infection
  3. Parasite
  4. Antimalarial agent 11

Antimalarial agent 11 (compound 1), a spirocyclic chromane, is a potent antimalarial agent. Antimalarial agent 11 exhibits excellent potency with an EC50 of 350 nM against the Chloroquine-resistant Dd2 strain. Antimalarial agent 11 has EC50s of 1.48 µM and 1.81 µM against D6 and ARC08-022 strains, respectively.

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Antimalarial agent 11 Chemical Structure

Antimalarial agent 11 Chemical Structure

CAS No. : 1214454-56-4

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Antimalarial agent 11 Related Antibodies

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Description

Antimalarial agent 11 (compound 1), a spirocyclic chromane, is a potent antimalarial agent. Antimalarial agent 11 exhibits excellent potency with an EC50 of 350 nM against the Chloroquine-resistant Dd2 strain. Antimalarial agent 11 has EC50s of 1.48 µM and 1.81 µM against D6 and ARC08-022 strains, respectively[1].

Molecular Weight

425.47

Formula

C25H25F2NO3
CAS No.
SMILES

OC(CN1CCC2(CC(O)C3=C(O2)C4=C(C=CC=C4)C=C3)CC1)C5=CC=C(F)C(F)=C5
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Antimalarial agent 11 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antimalarial agent 111214454-56-4Antimalarial agent11Antimalarial agent-11Parasitespirocyclic chromaneantimalarialChloroquineDd2 strainD6ARC08-022Inhibitorinhibitorinhibit

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