2. Anti-infection
  3. Bacterial
  4. Antitubercular agent-33

Antitubercular agent-33 is a 2-aminothiazole derivative, shows potent antintubercular activity against Mycobacterium tuberculosis (Mtb).

For research use only. We do not sell to patients.

Antitubercular agent-33 Chemical Structure

Antitubercular agent-33 Chemical Structure

CAS No. : 476317-29-0

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5 mg USD 120 In-stock
10 mg USD 195 In-stock
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Based on 1 publication(s) in Google Scholar

Antitubercular agent-33 Related Antibodies

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Description

Antitubercular agent-33 is a 2-aminothiazole derivative, shows potent antintubercular activity against Mycobacterium tuberculosis (Mtb)[1].

In Vitro

Antitubercular agent-33 (compound 49) exerts antitubercular effects with MIC values of 1.6-3.1 μM (in 7H9-glucose media) and 0.78 μM (in GAST media), respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antitubercular agent-33 Related Antibodies
Molecular Weight

326.33

Formula

C15H10N4O3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1=NC(C2=NC=CC=C2)=CS1)C3=CC=CC=C3[N+]([O-])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (306.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0644 mL 15.3219 mL 30.6438 mL
5 mM 0.6129 mL 3.0644 mL 6.1288 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0644 mL 15.3219 mL 30.6438 mL 76.6096 mL
5 mM 0.6129 mL 3.0644 mL 6.1288 mL 15.3219 mL
10 mM 0.3064 mL 1.5322 mL 3.0644 mL 7.6610 mL
15 mM 0.2043 mL 1.0215 mL 2.0429 mL 5.1073 mL
20 mM 0.1532 mL 0.7661 mL 1.5322 mL 3.8305 mL
25 mM 0.1226 mL 0.6129 mL 1.2258 mL 3.0644 mL
30 mM 0.1021 mL 0.5107 mL 1.0215 mL 2.5537 mL
40 mM 0.0766 mL 0.3830 mL 0.7661 mL 1.9152 mL
50 mM 0.0613 mL 0.3064 mL 0.6129 mL 1.5322 mL
60 mM 0.0511 mL 0.2554 mL 0.5107 mL 1.2768 mL
80 mM 0.0383 mL 0.1915 mL 0.3830 mL 0.9576 mL
100 mM 0.0306 mL 0.1532 mL 0.3064 mL 0.7661 mL
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Antitubercular agent-33 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitubercular agent-33476317-29-0Antitubercular agent33Antitubercular agent 33Bacterial2-aminothiazolenitroGAST media7H9-glucose mediaantitubercularMycobacterium tuberculosisInhibitorinhibitorinhibit

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