2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor 5-HT Receptor
  4. Apomorphine

Apomorphine  (Synonyms: (-)-Apomorphine)

Cat. No.: HY-12723 Purity: 99.48%
COA Handling Instructions

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Apomorphine is an orally active agonist of Dopamine receptor. Apomorphine can be used in study Parkinson, biphasic dyskinesias, urinary dysfunction,,dystonia, dyspnoea, anismus and belching.

For research use only. We do not sell to patients.

Apomorphine Chemical Structure

Apomorphine Chemical Structure

CAS No. : 58-00-4

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1 mg USD 140 In-stock
5 mg USD 350 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 6 publication(s) in Google Scholar

Other Forms of Apomorphine:

Apomorphine Related Antibodies

Top Publications Citing Use of Products

View All Dopamine Receptor Isoform Specific Products:

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Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

View All 5-HT Receptor Isoform Specific Products:

View All Isoforms
5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

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Description

Apomorphine is an orally active agonist of Dopamine receptor. Apomorphine can be used in study Parkinson, biphasic dyskinesias, urinary dysfunction,,dystonia, dyspnoea, anismus and belching[1].

Molecular Weight

267.32

Formula

C17H17NO2
CAS No.
Appearance

Solid

Color

Light green to green

SMILES

OC1=CC=C2C(C3=C4C(CCN(C)[C@]4([H])C2)=CC=C3)=C1O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 26 mg/mL (97.26 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7408 mL 18.7042 mL 37.4083 mL
5 mM 0.7482 mL 3.7408 mL 7.4817 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.48%

COA (251 KB) Elemental Analysis Report (109 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7408 mL 18.7042 mL 37.4083 mL 93.5209 mL
5 mM 0.7482 mL 3.7408 mL 7.4817 mL 18.7042 mL
10 mM 0.3741 mL 1.8704 mL 3.7408 mL 9.3521 mL
15 mM 0.2494 mL 1.2469 mL 2.4939 mL 6.2347 mL
20 mM 0.1870 mL 0.9352 mL 1.8704 mL 4.6760 mL
25 mM 0.1496 mL 0.7482 mL 1.4963 mL 3.7408 mL
30 mM 0.1247 mL 0.6235 mL 1.2469 mL 3.1174 mL
40 mM 0.0935 mL 0.4676 mL 0.9352 mL 2.3380 mL
50 mM 0.0748 mL 0.3741 mL 0.7482 mL 1.8704 mL
60 mM 0.0623 mL 0.3117 mL 0.6235 mL 1.5587 mL
80 mM 0.0468 mL 0.2338 mL 0.4676 mL 1.1690 mL
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Apomorphine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apomorphine58-00-4(-)-ApomorphineDopamine Receptor5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorParkinsonDopamine receptor AgonistBiphasic dyskinesiasUrinary dysfunctionInhibitorinhibitorinhibit

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