1. Induced Disease Models Products Metabolic Enzyme/Protease
  2. Immunology and Inflammatory Disease Models Endogenous Metabolite
  3. Paw Edema Models
  4. Arachidonic acid sodium salt

Arachidonic acid sodium salt  (Synonyms: Immunocytophyt sodium salt)

Cat. No.: HY-109590A Purity: 99.3%
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Arachidonic acid (Immunocytophyt) sodium salt is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid sodium salt also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid sodium salt improves cognitive response and cardiovascular function.

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Arachidonic acid sodium salt Chemical Structure

Arachidonic acid sodium salt Chemical Structure

CAS No. : 6610-25-9

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Based on 29 publication(s) in Google Scholar

Other Forms of Arachidonic acid sodium salt:

Top Publications Citing Use of Products

29 Publications Citing Use of MCE Arachidonic acid sodium salt

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Description

Arachidonic acid (Immunocytophyt) sodium salt is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid sodium salt also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid sodium salt improves cognitive response and cardiovascular function[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

Arachidonic acid sodium salt can be used to induce paw edema models[2].

Induction of Paw Edema Model[2]
Background
Principle: Injecting arachidonic acid into the hind paws of rats can induce rapid and sustained inflammatory responses.
Specific Mmodeling Methods
Rat: Lewis • male •
Administration: 0.5% • s.c. • single dose
Note
A single subcutaneous injection of 0.10 mL of arachidonic acid (dissolved in 0.2 M carbonate buffer with a pH value of 8.43-8.56) was administered into the right hind paw of male Lewis rats weighing 144-241 grams.
Modeling Indicators
Appearance Monitoring: Significant edema became apparent within 5 minutes, and the reaction reached its peak at 1 hour after injection.
Correlated Product(s): /
Opposite Product(s): phenidone (HY-W010144); SK&F86002 (HY-12511)

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Lew rats (4-week-old) induced arthritis[1]
Dosage: 0.07%, 0.15% or 0.32% in diet (w/w)
Administration: 4 weeks
Result: The Arachidonic acid content of phospholipids in the paw was significantly elevated in a dose-dependent manner.
Molecular Weight

326.45

Formula

C20H31NaO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation

Purity: 99.3%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Arachidonic acid sodium salt
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