Artemitin

Cat. No.: HY-N3017 Purity: 99.20%: FAQs
Data Sheet SDS COA Handling Instructions

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Artemitin is a flavonol found in Laggera pterodonta (DC.) Benth., with antioxidative, anti-inflammatory, and antiviral activity.

For research use only. We do not sell to patients.

Artemitin Chemical Structure

CAS No. : 479-90-3

Size	Price	Stock	Quantity
5 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
20 mg	USD 225	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Artemitin:

Artemitin (Standard) Get quote

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Description

Artemitin is a flavonol found in Laggera pterodonta (DC.) Benth., with antioxidative, anti-inflammatory, and antiviral activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	GI₅₀	2200 ng/mL Compound: 10	Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 11975496]
HepG2	IC₅₀	229 μM Compound: Artemetin	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 31784199]
HL-60	IC₅₀	6.44 μM Compound: VIII, 5-demethylhexaMF	Antiproliferative activity against HL60 after 24 hrs Antiproliferative activity against HL60 after 24 hrs	[PMID: 17391969]
Neutrophil	IC₅₀	> 10 μg/mL Compound: 9	Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-induced superoxide-anion generation incubated for 5 mins prior to FMLP/CB-challenge measured after 10 mins by spectrophotometry Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-induced superoxide-anion generation incubated for 5 mins prior to FMLP/CB-challenge measured after 10 mins by spectrophotometry	[PMID: 22429052]
Neutrophil	IC₅₀	> 10 μg/mL Compound: 9	Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-induced elastase release using Meo-Suc-Ala-Ala-Pro-Val-p-nitroanilide as substrate incubated for 5 mins prior to FMLP/CB-challenge by spectrophotometry Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-induced elastase release using Meo-Suc-Ala-Ala-Pro-Val-p-nitroanilide as substrate incubated for 5 mins prior to FMLP/CB-challenge by spectrophotometry	[PMID: 22429052]
PC-12	GI₅₀	2270 ng/mL Compound: 10	Cytotoxicity against rat PC12 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against rat PC12 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 11975496]
SH-SY5Y	IC₅₀	229 μM Compound: Artemetin	Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay	[PMID: 31784199]

Molecular Weight

388.37

Formula

C₂₀H₂₀O₈

CAS No.

479-90-3

Appearance

Solid

Color

White to yellow

SMILES

O=C1C2=C(O)C(OC)=C(OC)C=C2OC(C3=CC(OC)=C(OC)C=C3)=C1OC

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (128.74 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5749 mL	12.8743 mL	25.7486 mL
5 mM	0.5150 mL	2.5749 mL	5.1497 mL
10 mM	0.2575 mL	1.2874 mL	2.5749 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.73%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (251 KB) HNMR (257 KB) LCMS (92 KB)

Handling Instructions (2659 KB)

References

[1]. Han X, et al. Development of an LC-MS/MS-based assay to determine artemitin in rat plasma and its application in a pharmacokinetic study. Biomed Chromatogr. 2018 Dec;32(12):e4356. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5749 mL	12.8743 mL	25.7486 mL	64.3716 mL
	5 mM	0.5150 mL	2.5749 mL	5.1497 mL	12.8743 mL
	10 mM	0.2575 mL	1.2874 mL	2.5749 mL	6.4372 mL
	15 mM	0.1717 mL	0.8583 mL	1.7166 mL	4.2914 mL
	20 mM	0.1287 mL	0.6437 mL	1.2874 mL	3.2186 mL
	25 mM	0.1030 mL	0.5150 mL	1.0299 mL	2.5749 mL
	30 mM	0.0858 mL	0.4291 mL	0.8583 mL	2.1457 mL
	40 mM	0.0644 mL	0.3219 mL	0.6437 mL	1.6093 mL
	50 mM	0.0515 mL	0.2575 mL	0.5150 mL	1.2874 mL
	60 mM	0.0429 mL	0.2146 mL	0.4291 mL	1.0729 mL
	80 mM	0.0322 mL	0.1609 mL	0.3219 mL	0.8046 mL
	100 mM	0.0257 mL	0.1287 mL	0.2575 mL	0.6437 mL

Artemitin Related Classifications

Inflammation/Immunology Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Artemitin479-90-3AntibioticInhibitorinhibitorinhibit

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Artemitin

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Complete Stock Solution Preparation Table

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