2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. Ascorbyl tetra-2-hexyldecanoate

Ascorbyl tetra-2-hexyldecanoate  (Synonyms: tetra-isopalmitoyl Ascorbic acid; IPAA; Tetrahexyldecyl Ascorbate)

Cat. No.: HY-133079 Purity: ≥98.0%
SDS COA Handling Instructions Technical Support

Ascorbyl tetra-2-hexyldecanoate (tetra-isopalmitoyl Ascorbic acid; IPAA) is a lipophilic derivative of vitamin C (L-ascorbic acid). Ascorbyl tetra-2-hexyldecanoate (100 μM ) can prevent the decrease in viability of HaCaT keratinocytes induced by UVB, hydrogen peroxide, or tert-butyl hydroperoxide, and reduce the production of IL-1α and prostaglandin E2 (PGE2). Topical application of ascorbyl tetra-2-hexyldecanoate (1%) increases epidermal viability thickness, stratum corneum water content, and skin smoothness, and reduces skin roughness in hairless mice. Ascorbyl tetra-2-hexyldecanoate can be used to develop skin whitening agents in the beauty industry.

For research use only. We do not sell to patients.

Ascorbyl tetra-2-hexyldecanoate Chemical Structure

Ascorbyl tetra-2-hexyldecanoate Chemical Structure

CAS No. : 183476-82-6

Size Price Stock Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Liquid
1 g In-stock
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10 g Get quote
50 g   Get quote  

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Based on 1 publication(s) in Google Scholar

Ascorbyl tetra-2-hexyldecanoate Related Antibodies

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DP EP FP IP TXA2/TP TXB2

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Description

Ascorbyl tetra-2-hexyldecanoate (tetra-isopalmitoyl Ascorbic acid; IPAA) is a lipophilic derivative of vitamin C (L-ascorbic acid). Ascorbyl tetra-2-hexyldecanoate (100 μM ) can prevent the decrease in viability of HaCaT keratinocytes induced by UVB, hydrogen peroxide, or tert-butyl hydroperoxide, and reduce the production of IL-1α and prostaglandin E2 (PGE2). Topical application of ascorbyl tetra-2-hexyldecanoate (1%) increases epidermal viability thickness, stratum corneum water content, and skin smoothness, and reduces skin roughness in hairless mice. Ascorbyl tetra-2-hexyldecanoate can be used to develop skin whitening agents in the beauty industry.

Molecular Weight

1129.76

Formula

C70H128O10
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C1O[C@H]([C@@H](OC(C(CCCCCC)CCCCCCCC)=O)COC(C(CCCCCC)CCCCCCCC)=O)C(OC(C(CCCCCC)CCCCCCCC)=O)=C1OC(C(CCCCCC)CCCCCCCC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (177.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8851 mL 4.4257 mL 8.8514 mL
5 mM 0.1770 mL 0.8851 mL 1.7703 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8851 mL 4.4257 mL 8.8514 mL 22.1286 mL
5 mM 0.1770 mL 0.8851 mL 1.7703 mL 4.4257 mL
10 mM 0.0885 mL 0.4426 mL 0.8851 mL 2.2129 mL
15 mM 0.0590 mL 0.2950 mL 0.5901 mL 1.4752 mL
20 mM 0.0443 mL 0.2213 mL 0.4426 mL 1.1064 mL
25 mM 0.0354 mL 0.1770 mL 0.3541 mL 0.8851 mL
30 mM 0.0295 mL 0.1475 mL 0.2950 mL 0.7376 mL
40 mM 0.0221 mL 0.1106 mL 0.2213 mL 0.5532 mL
50 mM 0.0177 mL 0.0885 mL 0.1770 mL 0.4426 mL
60 mM 0.0148 mL 0.0738 mL 0.1475 mL 0.3688 mL
80 mM 0.0111 mL 0.0553 mL 0.1106 mL 0.2766 mL
100 mM 0.0089 mL 0.0443 mL 0.0885 mL 0.2213 mL
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Ascorbyl tetra-2-hexyldecanoate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ascorbyl tetra-2-hexyldecanoate183476-82-6tetra-isopalmitoyl Ascorbic acid IPAA Tetrahexyldecyl AscorbateProstaglandin ReceptorInhibitorinhibitorinhibit

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