2. Immunology/Inflammation Autophagy Anti-infection
  3. COX Autophagy Mitophagy Virus Protease
  4. Aspirin-d4

Aspirin-d4  (Synonyms: Acetylsalicylic Acid-d4; ASA-d4)

Cat. No.: HY-14654S1 Purity: 98.08%
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Aspirin-d4 is the deuterium labeled Aspirin. Aspirin is a non-selective and irreversible inhibitor of COX-1 and COX-2 with IC50s of 5 and 210 μg/mL[1][2].

For research use only. We do not sell to patients.

Aspirin-d<sub>4</sub> Chemical Structure

Aspirin-d4 Chemical Structure

CAS No. : 97781-16-3

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1 mg USD 108 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Aspirin-d4:

Aspirin-d4 Related Antibodies

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Description

Aspirin-d4 is the deuterium labeled Aspirin. Aspirin is a non-selective and irreversible inhibitor of COX-1 and COX-2 with IC50s of 5 and 210 μg/mL[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aspirin-d4 Related Antibodies
Molecular Weight

184.18

Formula

C9H4D4O4
CAS No.
Unlabeled CAS

50-78-2
Appearance

Solid

Color

White to off-white

SMILES

OC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])OC(C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (542.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4295 mL 27.1474 mL 54.2947 mL
5 mM 1.0859 mL 5.4295 mL 10.8589 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.4295 mL 27.1474 mL 54.2947 mL 135.7368 mL
5 mM 1.0859 mL 5.4295 mL 10.8589 mL 27.1474 mL
10 mM 0.5429 mL 2.7147 mL 5.4295 mL 13.5737 mL
15 mM 0.3620 mL 1.8098 mL 3.6196 mL 9.0491 mL
20 mM 0.2715 mL 1.3574 mL 2.7147 mL 6.7868 mL
25 mM 0.2172 mL 1.0859 mL 2.1718 mL 5.4295 mL
30 mM 0.1810 mL 0.9049 mL 1.8098 mL 4.5246 mL
40 mM 0.1357 mL 0.6787 mL 1.3574 mL 3.3934 mL
50 mM 0.1086 mL 0.5429 mL 1.0859 mL 2.7147 mL
60 mM 0.0905 mL 0.4525 mL 0.9049 mL 2.2623 mL
80 mM 0.0679 mL 0.3393 mL 0.6787 mL 1.6967 mL
100 mM 0.0543 mL 0.2715 mL 0.5429 mL 1.3574 mL
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Aspirin-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aspirin-d497781-16-3Acetylsalicylic Acid-d4ASA-d4COXAutophagyMitophagyVirus ProteaseCyclooxygenaseMitochondrial AutophagyInhibitorinhibitorinhibit

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