Autophagy/REV-ERB-IN-1 hydrochloride

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Autophagy/REV-ERB-IN-1 hydrochloride (Compound 24) is a dual autophagy and REV-ERB inhibitor with anticancer activity. Autophagy/REV-ERB-IN-1 (hydrochloride) has improved potency in blocking autophagy, enhanced toxicity against cancer cells. Autophagy/REV-ERB-IN-1 (hydrochloride) can be used for the research for melanoma.

For research use only. We do not sell to patients.

Autophagy/REV-ERB-IN-1 hydrochloride Chemical Structure

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Description	Autophagy/REV-ERB-IN-1 hydrochloride (Compound 24) is a dual autophagy and REV-ERB inhibitor with anticancer activity. Autophagy/REV-ERB-IN-1 (hydrochloride) has improved potency in blocking autophagy, enhanced toxicity against cancer cells. Autophagy/REV-ERB-IN-1 (hydrochloride) can be used for the research for melanoma^[1].
Molecular Weight	457.43
Formula	C₂₄H₃₂Cl₂F₂N₂
SMILES	FC1=CC=C(CNC2(C3=CC=C(F)C=C3)CCCC2)C=C1CC4CCNCC4.Cl.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (267 KB) Handling Instructions (2659 KB)
References	[1]. Palomba M, et al. Identification of a Dual Autophagy and REV-ERB Inhibitor with in Vivo Anticancer Efficacy. J Med Chem. 2024 Jan 11;67(1):349-379. [Content Brief]