1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. BChE-IN-26

BChE-IN-26 (Compound 7b) is a selective AChE and BChE inhibitor with Ki value of 35 μM and 1.6 μM. BChE-IN-26 has cytotoxicity to human neuroblastoma (SH-SY5Y) cell line. BChE-IN-26 can be used for the research of Alzheimer’s disease.

For research use only. We do not sell to patients.

BChE-IN-26 Chemical Structure

BChE-IN-26 Chemical Structure

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Description

BChE-IN-26 (Compound 7b) is a selective AChE and BChE inhibitor with Ki value of 35 μM and 1.6 μM. BChE-IN-26 has cytotoxicity to human neuroblastoma (SH-SY5Y) cell line. BChE-IN-26 can be used for the research of Alzheimer’s disease[1].

IC50 & Target

AChE

35 μM (Ki)

BChE

1.6 μM (Ki)

Molecular Weight

394.29

Formula

C19H21Cl2N3O2

SMILES

ClC1=C(CN2CCN(CC3=C(Cl)C=CC=C3)CC2C(NO)=O)C=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
BChE-IN-26
Cat. No.:
HY-161156
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