2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. BChE-IN-26

BChE-IN-26 (Compound 7b) is a selective AChE and BChE inhibitor with Ki value of 35 μM and 1.6 μM. BChE-IN-26 has cytotoxicity to human neuroblastoma (SH-SY5Y) cell line. BChE-IN-26 can be used for the research of Alzheimer’s disease.

For research use only. We do not sell to patients.

BChE-IN-26 Chemical Structure

BChE-IN-26 Chemical Structure

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BChE-IN-26 Related Antibodies

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Description

BChE-IN-26 (Compound 7b) is a selective AChE and BChE inhibitor with Ki value of 35 μM and 1.6 μM. BChE-IN-26 has cytotoxicity to human neuroblastoma (SH-SY5Y) cell line. BChE-IN-26 can be used for the research of Alzheimer’s disease[1].

IC50 & Target

AChE

35 μM (Ki)

BChE

1.6 μM (Ki)

Molecular Weight

394.29

Formula

C19H21Cl2N3O2
SMILES

ClC1=C(CN2CCN(CC3=C(Cl)C=CC=C3)CC2C(NO)=O)C=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BChE-IN-26 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BChE-IN-26Cholinesterase (ChE)Alzheimer’s diseasecytotoxicityInhibitorinhibitorinhibit

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